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How To Get A Prescription For Medical Cannabis In The UK
Did you know that just 6.5% of all cannabis-based medicines prescribed in 2019 were filled out via the NHS?
Coming the year after the law changed to allow doctors to legally prescribe cannabis medicines, the change in mindset for many specialist doctors moved much slower than the law.
Even now over two years on, the estimated number of prescriptions on the NHS is still believed to be in the low hundreds, while around 1.4 million people in the UK are using cannabis to treat their own medical conditions.
However, according to the Misuse of Drugs Act 1971, cannabis is a Class B drug and so cannot be legally used without a prescription.
Remember that police forces may get involved if they find you buying cannabis illegally, no matter what the purpose.
Many NHS doctors are still cautious to prescribe medical cannabis, despite the overwhelming evidence from clinical trials for a variety of medical conditions, such as multiple sclerosis and chronic pain.
This is largely due to guidelines from the National Institute for Health and Care Excellence (NICE), which continue to state that there is a lack of evidence to support NHS cannabis prescriptions, despite such treatment working for thousands of people across the UK.
Nonetheless, the reality for many is that NHS prescriptions are not a realistic avenue to explore cannabis-based medicines.
Instead, many across the country are turning to private medical cannabis clinics to offer cost-effective cannabis medicines within a timeframe that works for them.
What are the rules around cannabis prescriptions?
Medical cannabis refers to any medication that contains cannabis and has been legal for specialist doctors to prescribe since November 2018.
This means that GPs cannot fill out a cannabis prescription, but they can refer patients to the right medical professional in order to do so if they agree that a prescription is the right course of action.
These decisions are still largely made on a case-by-case basis. By law, a medical cannabis prescription can only be given out “when the patient has an unmet special clinical need that cannot be met by licensed products”.
That means that patients will need to pursue other forms of treatment before being able to try prescribed medical cannabis. Products such as CBD or hemp oil can be sold legally as food supplements and are not subject to the same laws as medical cannabis.
How to get medical cannabis in the UK
For many people in the UK, the only realistic way to access cannabis for medical purposes is through a private prescription. Finding a clinic that suits you should therefore be your first step.
How to fund a private cannabis prescription
Of course, private medical clinics are not always financially accessible to everyone. Nonetheless, efforts are being made to provide everyone who needs it with access to cannabis at a cost that they can afford.
For example, Project Twenty21 allows eligible patients to access treatment at a capped price. In return, the effects of the treatment will be tracked by Drug Science and go on to provide evidence for NHS funding of cannabis treatment.
Many clinics across the UK have partnered with Project Twenty21 in order to make medical cannabis as easily accessible as possible. It’s hoped that the data collected from Drug Science will also help to change NICE’s guidelines and make cannabis-based medicines more widely available in the future.
What to expect from your appointment
When you first talk with someone from a medical cannabis clinic, you will be asked to share access to your medical records. This is to ensure that you have a condition that entitles you to a cannabis prescription and enables the medical professionals to find the right program for you down the line.
To speed up the process, it’s a good idea to contact your GP ahead of time and request a copy of your Summary Care Record (SCR), which includes, at a minimum:
- Any current medication(s)
- Allergies and details of any previous bad reactions to medicines
- Your name, address, date of birth, and NHS number
If a diagnosis of the condition that entitles you to a cannabis prescription is not included in your SCR, you can also request a referral letter from your GP. The key requirement is that you must provide a confirmed diagnosis of one or more qualifying conditions. If you are uncertain about any part of this, the clinic will likely be able to assist you.
Once your medical records have been shared, you will need to require a consultation with someone from your chosen clinic. This will either be in person or via a video call and your consultant will conduct an assessment with you.
Questions within the assessment will cover what treatments you might have tried in the past, why they haven’t worked, what symptoms from your condition you are experiencing, and how your condition is affecting your life day-to-day.
The consultant will also likely ask if you’ve used cannabis for medicinal purposes before and what the effects were. All of these questions are to identify whether cannabis is the right course of action for you.
In some cases, your case may also be presented and discussed with a multidisciplinary team, to get a full sense of how the treatment may affect you and your condition moving forward. Remember that you have the right for anything you discussed to be left off your records if you would like to.
This is not only the time for your consultant to get to know you but also for you to get to know your chosen clinic. If you have any concerns, questions, or fears about the process or about your cannabis prescription in general, this is the time to ask them.
It’s a good idea to take notes throughout your consultation so that you have all the information discussed to hand later on. Lots of topics may be discussed, so it’s easy to forget some points later on.
Getting medical cannabis on Project Twenty21
Project Twenty21 is an initiative designed to allow eligible patients to access treatment at a capped price. In return, the effects of the treatment will be tracked by Drug Science and go on to provide evidence for NHS funding of cannabis treatment.
Many clinics, including The Medical Cannabis Clinics, across the UK, have partnered with Project Twenty21 in order to make medical cannabis as easily accessible as possible. It’s hoped that the data collected from Drug Science will also help to change NICE’s guidelines and make cannabis-based medicines more widely available in the future.
With Project Twenty21, different clinics charge different prices, ranging from £90 – £200 for an Initial Consultation and a Follow-up Consultation costs between £60 – £150. At The Medical Cannabis Clinics, we believe that everyone eligible should be able to get access to the medication they need, and so aim to keep costs as low as possible for our patients and only charge £90 for an initial consultation. Follow-up consultations are charged at £65.
Can I get a prescription for medical cannabis?
Cannabis can help to treat symptoms for a wide range of conditions. The private sector still adheres to the same laws as the NHS, and so can prescribe cannabis-based products for specific conditions, including:
- Chronic pain
These are to name just a few. You can find a full list of the conditions that are eligible for a medical cannabis prescription here or talk to your GP to see if you can get a referral letter. You are required to have tried two other forms of medication in order to be eligible for this treatment option.
Can a private doctor prescribe cannabis?
Cannabis prescriptions are currently most often provided through private clinics than via any other means in the UK. It’s often the faster way to get a medical cannabis prescription.
You can book an appointment with a specialist now through The Medical Cannabis Clinics in just a few minutes. Appointments start from just £70 and, once you’ve had a consultation with your doctor, you can receive your prescription at a local pharmacy of your choice. If you have any questions about how to get medical cannabis in the UK, don’t hesitate to reach out to one of our Patient Advisors.
Frequently asked questions
How much does medical cannabis cost in the UK?
Although the cost of medical cannabis does of course vary from person to person, depending on their condition and dose, the cost of a monthly dose starts from £75 to £120 per 10 grams at The Medical Cannabis Clinics. Medication is usually prescribed in doses of around 1 gram per day, 7 grams per week, and 30 grams per month, on average.
Where does medical cannabis come from in the UK?
Medical cannabis must be sourced from licensed producers according to UK law. Different brands of medical cannabis may source their products from different locations, often from countries in the EU and Africa.
Can anyone get medical cannabis on prescription in the UK?
You can only get medical cannabis on prescription in the UK if you have a specific eligible condition. The people most likely to be prescribed medical cannabis on the NHS are children and adults with rare, severe forms of epilepsy, adults with vomiting or nausea caused by chemotherapy, and people with muscle stiffness and spasms caused by MS. Eligible patients must also have sought other forms of treatment previously.
Can I apply for medical cannabis in the UK?
If you have been diagnosed with one of these qualifying conditions , you may be able to apply for medical cannabis in the UK. The first step is to speak to your GP and see if they will refer you to a specialist doctor or book a consultation with a private medical cannabis clinic.
Can you get medical cannabis in the UK?
If you are eligible, you will be able to discuss a treatment plan with a specialist doctor or medical cannabis clinic consultant to find the right dose for you and your condition.
Who qualifies for medical cannabis?
You must have a qualifying condition, including a number of pain conditions, neurological conditions, psychiatric conditions, gastroenterological conditions, side effects from cancer treatment, and more. You must also have sought treatment from other means.
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Cannabis-based products for medicinal use: Frequently asked questions
A set of clinical frequently asked questions (FAQs) to provide further support to prescribers.
There are three broad requirements that a product should satisfy:
- The product is or contains cannabis, cannabis resin, cannabinol or a cannabinol derivative
- It is produced for medicinal use in humans; and
- It is a product that is regulated as a medicinal product, or an ingredient of a medicinal product.
The definition is necessarily broad to take account of the range of preparations which are cannabis-based that have been used for therapeutic purposes and to ensure that raw products/ingredients and intermediate products are captured. This is essential to ensure that where there is a clinical need, a patient will be able to access appropriate cannabis-based medicines and/or products can be made to meet any prescription.
‘Pure’ cannabidiol (CBD) only based products (including synthetic versions) are not classified as a cannabis-based product for medicinal use and are not controlled drugs as they contain very small amounts of THC. To be exempt from scheduling a product will need to fulfil the three limbs of the Exempt Product definition as outlined in the law.
There are three main groups of chemical compounds that fall within the broad category of ‘synthetic cannabinoids’:
- Synthetic compounds which are identical in structure to naturally occurring cannabinoids such as delta-9-tetrahydrocannabinol (THC) e.g. Dronabinol.
- Synthetic compounds structurally related to naturally occurring cannabinoids that have been developed to mimic naturally occurring cannabinoids such as THC e.g. Nabilone.
- Synthetic compounds not structurally related to naturally occurring cannabinoids but which bind to cannabinoid receptors in the body.
With respect to group 1 compounds, Dronabinol has been developed as a medicinal product. Dronabinol is not available as a licensed medicine in the UK. In addition, in group 2, Nabilone has also been developed for medicinal use and is available as a licensed medicinal product. Group 3 synthetic compounds not structurally related to naturally-occurring cannabinoids but which bind to cannabinoid receptors in the body are not available as licensed medicinal products. Many of the compounds in group 3 have frequently been found in illicit street products referred to by the street names of Spice and Black Mamba and are predominantly new psychoactive substances (NPS). There is clear evidence of significant harm and several deaths associated with their illicit use.
The Advisory Council on the Misuse of Drugs (ACMD) has particular concerns with compounds falling within group 3 and others within group 2, with the exception of Nabilone, and is of the view that further research into this complex group of diverse substances is important, given the associated potency and harms.
This group of new psychoactive substances is being considered by the ACMD as part of their longer-term review.
Due to the limited evidence base and their unlicensed nature, prescribing of cannabis-based products for medicinal use is restricted to only those clinicians listed on the Specialist Register of the General Medical Council.
Any decision to prescribe must take into account the relevant GMC guidance and the relevant NHS Trust governance procedures for unlicensed medicines in the normal way. In addition, a Specialist on the General Medical Council Register should only prescribe within their own area of practice and training, and the decision to prescribe should generally be agreed by the multidisciplinary team. Adhering to the normal medicines governance systems not only supports good clinical practice but also offers liability coverage for NHS employees in prescribing an unlicensed medicine and importantly, is safer for patients.
A GP may make a referral to a specialist doctor on the General Medical Council’s ‘Specialist Register’ once the patient reaches the appropriate point in their treatment pathway.
The law requires that these products be supplied under either the prescription or direction of a clinician on the General Medical Council’s Specialist Register. It is important to ensure that clinical specialists with the appropriate expertise are able to make treatment decisions in their patient’s best interest, and that decisions about prescribing are in the hands of expert clinicians led by evidence on quality, safety and effectiveness, balancing the benefits that might be accrued for a particular patient against the products proven harms.
Private Doctors who are on the General Medical Council’s specialist register are now legally able to prescribe cannabis-based products for medicinal use. This is the same for NHS and private providers. In the NHS, decisions to prescribe should generally be the result of multidisciplinary discussion. The Chief Medical Officer expects clinicians in a non-NHS setting to follow equivalent processes for prescribing unlicensed special medicines.
Specialist Doctors, whether working for the NHS or not, will receive support and guidance on the evidence for the use of cannabis-based products for medicinal use, and the circumstances in which they may be prescribed. This is in the form of the interim clinical guidance (from the BPNA, RCP and ABN), the MHRA specials guidance and the NICE clinical guideline.
Prescribing by both private and NHS providers will be monitored by local controlled drugs accountable officers.
Specialist doctors wishing to prescribe this privately outside of a hospital environment will need to contact the local lead Controlled Drugs Accountable Officer for a Prescriber Identification Number.
The law requires that these products be supplied under either the prescription or direction of a clinician on the General Medical Council’s Specialist Register.
However, whilst it is possible for a GP to continue prescribing legally, it is advised that all prescriptions will need to be initiated and signed by a specialist doctor. Consideration will be given to how shared care arrangements should or could work, including determining whether it is indeed appropriate to have such arrangements in place. If a doctor prescribes a medicine under shared care arrangements, he or she accepts clinical and professional responsibility for that prescribing decision.
The law has been drafted such that a specialist needs to be responsible for the decision to prescribe. However, the law does allow other prescribers to continue prescribing once the decision to prescribe has been made by a specialist.
There are existing arrangements permitting doctors not on the specialist register but working under the direction of a specialist within a hospital setting (e.g. speciality registrars, supplementary prescribers, non-medical independent prescribers etc.) to continue prescribing, once patients have become established on a particular treatment with no problems.
In general, however it is expected that patients receiving these products to remain under the direct care of a specialist doctor (i.e. initiation and continued prescribing) in the first instance.
Private prescriptions from outside the UK will not be permissible as the law indicates that prescribing of cannabis-based products for medicinal use is restricted to only those clinicians listed on the Specialist Register of the General Medical Council.
UK Regulations mean that Schedule 2 and/or 3 controlled drugs and unlicensed medicines may not be supplied on a prescription authorised by an EEA practitioner. This is not unique to cannabis. In addition any prescription that does not comply with the UK requirements cannot be used to lawfully import a product for personal use from another jurisdiction.
As with prescribing any other unlicensed medicine, it is a clinical decision to determine the most appropriate medication or course of treatment to prescribe for a patient, having taken into account the patient, the clinical condition, the clinical evidence of efficacy and safety and the suitability of licensed medicines.
The National Institute for Health and Care Excellence (NICE) has published a clinical guideline on the prescribing of cannabis-based products for medicinal use in humans. This guidance was published in November, with further Technology Appraisals on use of Epidyolex® published in December 2019. These include recommendations for:
- people with chronic pain
- people with intractable nausea and vomiting
- people with spasticity
- people with severe treatment-resistant epilepsy.
In the interim to this guidance being published the British Paediatric Neurology Association (BPNA) had developed clinical advice on the use of cannabis-based products for medicinal use in paediatric patients with certain forms of severe epilepsy, and the Royal College of Physicians (RCP) had developed additional advice around prescribing of cannabis-based products for medicinal use in intractable chemotherapy induced nausea and vomiting, and chronic cancer pain.
The Association of British Neurologists (ABN) had developed guidance on the use of cannabis-based products for medicinal use in adult patients with neurological conditions. This guidance is now available and covers use in rare epilepsies and MS related spasticity.
Advice produced by the Professional Organisations has now been superseded by issuing of the NICE guidance as outlined above
No. Doctors should always first consider prescribing medicines that are licensed for the specific condition that the patient presents with. This is because these products have been tested for quality, safety and efficacy by the regulators for the indication they are prescribed for and are subject to the quality assurance arrangements that apply to all licensed medicines when they are manufactured. If this is not possible then the next option would be an off-label use of a licensed medicine, again because these will have been subject to those quality assurance arrangements, but the doctor has to be confident that the medicine would be appropriate for the specific indication and the patient, that it is being prescribed for.
Prescribing an unlicensed product should be considered third and only if an individual patient has exceptional clinical needs that cannot be met by a licensed or off-label medicine.
The BPNA guidance recommends that CBD (Epidiolex®) should be the default choice when considering prescription of a cannabis-derived medicinal product in intractable epilepsy in children. They do not recommend prescribing other non-licensed cannabis-derived medicinal products, which includes all artisanal cannabis oils, whether or not they comply with good manufacturing practice (GMP) or good distribution practice (GDP) standards.
Cannabidiol oral solution (Epidyolex®) is a CBD product that has been through randomised controlled trials for two epilepsy syndromes (Dravets syndrome and Lennox-Gastaut syndrome). It has recently been approved for a European marketing authorisation by the European Medicines Agency (EMA) for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome. From 1 October 2019, Epidyolex® will be classified as a Schedule 2 controlled drug (CD) in the UK rather than being exempt from scheduling (an ‘Exempt Product’). This change is being made to reflect the trace levels of THC in the medicine. Prior to licensing, Epidyolex® was available through compassionate use and extended access programmes. These are now closed to new patients.
NICE has published Technology Appraisals for the use of cannabidiol (Epidyolex®) for severe treatment-resistant epilepsies. The appraisals look at the clinical and cost effectiveness of cannabidiol in conjunction with clobazam for adjuvant treatment of seizures associated with Lennox-Gastaut and Dravet syndromes. Both appraisals recommend cannabidiol with clobazam as an option for treating seizures associated with these syndromes in people aged 2 years and older, subject to adequate monitoring and supply arrangements.
Because the only evidence for efficacy and safety in childhood epilepsies relates to use of pure cannabidiol (Epidyolex®). Currently there is no good evidence that products that contain THC are either safe or efficacious and there is a concern about the effect of THC on the developing brain. There is evidence that chronic high exposure to THC during recreational cannabis use can affect brain development, structure and mental health.
Cannabis has many active chemical constituents and two of these constituents, tetrahydrocannabinol (THC) and cannabidiol (CBD) have been investigated the most in respect of their medicinal value. THC is the major psychoactive constituent of cannabis and is considered responsible for giving so called “highs” to users of cannabis. CBD on the other hand, is not psychoactive. “Pure CBD” is not a controlled drug for the purposes of the 1971 Misuse of Drugs Act.
Products falling within Schedule 2 will contain varying quantities and ratios of THC and CBD and may be available in a range of pharmaceutical forms.
The BPNA advise that any child who is already taking a cannabis-based product for medicinal use containing THC that is having an apparently beneficial effect should transition to pure cannabidiol (Epidyolex®) as there is stronger evidence of effectiveness and a lower risk of long-term side effects than for products containing THC. However as with all treatment decisions, it is ultimately the responsibility of the patients’ Paediatric Neurologist, in discussion with the patient and their family, to determine the best treatment options, taking into account the emerging evidence and the patients’ individual clinical circumstances.
The recommendations have been jointly produced by the Royal College of Physicians (RCP), the Royal College of Radiologists (RCR) and in liaison with the Faculty of Pain Medicine of the Royal College of Anaesthetists. The guidance covers cannabis-based products for medicinal use for chemotherapy induced nausea and vomiting and chronic pain (cancer pain and chronic neuropathic pain).
They recommend that for chemotherapy induced nausea and vomiting, cannabis-based products for medicinal use should remain an option for those who have failed standard therapies. They should not be used as a first-line treatment. They do not recommend use of cannabis-based medicinal products for chronic pain as there is no robust evidence supporting this.
The current evidence for use of cannabis-based products for pain is not sufficiently developed yet; whilst individual patients may perceive benefit; this hasn’t been fully tested in comparative randomised controlled trials in large numbers of patients. Potential harms of using cannabis-based treatments for medicinal use in the long term have also not been studied. There are currently no licensed cannabis-based products available for use in pain.
A recent Cochrane review for neuropathic pain states that ‘there is a lack of good evidence that any cannabis-derived product works for any chronic neuropathic pain’
Rescheduling of these products makes it easier for clinical trials to take place to support furthering our understanding, as the evidence base develops following more research being carried out and as products become licensed, this position will be reviewed.
The ABN guidance recommends that for both Dravets syndrome and Lennox-Gastaut syndrome the BPNA guidance is consulted and they recommend that cannabidiol should be prescribed in these cases.
For other types of epilepsies, they recommend that at present that there is either no or very little evidence for benefit in other forms of epilepsies. Until there is more evidence the ABN guidance advises extreme caution if these products are being considered for any other form of epilepsy.
The RCP guidance covers use in chronic neuropathic pain which is the predominant type of pain that MS patients experience. Use for chronic pain is currently not recommended as there is insufficient evidence.
There is also some evidence for use of cannabis-based products for MS related spasticity, as outlined in the CMO report. There is a licensed product available in the UK for use in MS related spasticity – Sativex®. This has been through the licensing process and should be used over any unlicensed cannabis-based products for medicinal use; NICE have now published a guideline on Cannabis-Based Medicinal Products. The guideline recommends offering a 4-week trial of THC:CBD spray (Sativex®) to treat moderate to severe spasticity in adults with multiple sclerosis, if other pharmacological treatments for spasticity are not effective.
In Scotland, the manufacturer has never made a submission to the Scottish Medicines Consortium and so Sativex® is not routinely available. In Wales Sativex® is available for use for MS related spasticity.
The ABN guidance suggests that cannabis-based products for medicinal use are used only in people who have had an unsatisfactory response to conventional spasticity drugs e.g. Sativex® – noting NICE and equivalent guidelines on use.
In line with routine clinical practice patients may wish to seek a second opinion and should be supported to do so. Clinicians should refer patients for a second opinion using their established protocols. Further information for patients on second or further opinions is available via the NHS website.
If it is not possible to obtain a second or further opinion using established protocols then please contact your NHS England Regional Medical Director who will be able to offer further advice around a referral route.
No medicine is completely risk free. In the case of products supplied as part of a clinical trial or which is the subject of a Marketing Authorisation, the Medicines and Healthcare Products Regulatory Agency (MHRA) will have assessed the product in line with its normal procedures for safety, quality and efficacy.
Like all other unlicensed medicines imported into or manufactured in the UK, products can only be sourced from reputable suppliers and manufacturers licensed by the MHRA or equivalent organisations of the country from where the product is being sourced. Licence holders in the UK are inspected for compliance with good manufacturing practice standards.
No. These are special medicines and any supplier that has the appropriate MHRA and HO licences and meets the conditions set out in the MHRA guidance can supply. MHRA and DHSC have provided information to Procurement Lead Pharmacists in the NHS. DHSC will keep this information updated until supply becomes established.
Further information will be available from local Procurement Lead Pharmacists.
By rescheduling, we are making it easier to conduct clinical trials on these products. The evidence base for these products is still developing and these changes to the law will encourage further research. The National Institute for Health Research has now issued a call for research proposals to increase our knowledge in this area. The call covers proposals for primary clinical research to evaluate the safety and clinical efficacy or clinical effectiveness of cannabis-based products for medicinal use in humans and was open until July 2019. Applications are currently being considered.
NHS England has commissioned and developed an e-learning training with Health Education England and the University of Birmingham, on cannabis and cannabis based products for medicinal use which all healthcare professionals can access.
This package includes the pharmacology of cannabis, legislation governing medical use and therapeutic areas and evidence for its use. The module will be updated as more information becomes available.
In March 2019, the Secretary of State for Health and Social Care commissioned NHS England and NHS Improvement to review NHS systems and processes to identify and recommend any action necessary to address any barriers to clinically appropriate prescribing of cannabis-based products for medicinal use (CBPMs) on the NHS. The findings and recommendations are available in the document ‘Barriers to accessing cannabis-based products for medicinal use on NHS prescription‘.
The report outlines a number of recommendations aimed at addressing the barriers to clinically appropriate prescribing. These include the establishment of a UK-wide paediatric network to support discussion of complex cases and assist in evidence generation, clinical trials (pending ethical review) and an alternative study for those already in receipt of a CBPM. NHS England and NHS Improvement will work with other national organisations to implement the recommendations and ensure that where it is clinically appropriate, clinicians feel supported to prescribe a cannabis-based product for medicinal use on the NHS.
The Refractory Epilepsy Specialist Clinical Advisory Service (RESCAS) is an independent specialist clinical network that provides evidence-based advice to clinicians treating patients with refractory epilepsy. This UK-wide panel is able to provide advice impartially on a range of treatment options for individuals with refractory epilepsy, based on clinical evidence, knowledge and experience.
This ‘clinician to clinician’ support and advice is available to tertiary paediatric neurology consultants, who jointly care for patients with other clinicians, as part of a multi-disciplinary team.
The advisory network is independent and is hosted by Great Ormond Street Hospital for Children NHS Foundation Trust.