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cbd and nerve pain

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Side effects caused by CBD can include feeling tired or sleepy, diarrhea and reduced appetite [VanDolah 2019] [15] .

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A 2012 literature review published in the Journal of Experimental Medicine examined at least one way that cannabinoids suppress inflammatory and neuropathic pain, by targeting alpha-3 glycine receptors. Citing the difficulty of treating neuropathic pain, the researchers also noted that CBD might be able to address the persistent discomfort associated with a range of diseases.

When it comes to examining the role of CBD in neuropathic pain, human studies are few and far between. The most compelling evidence, however, comes from the study of a cannabis-derived pharmaceutical called Nabiximols, which contains equal parts CBD and THC. Clinical trials in the United Kingdom and Canada have demonstrated the ability of combined CBD/THC to relieve neuropathic pain.

Research overview

CBD may relieve neuropathic pain by activating the brain’s serotonin receptors. Photo by: Gina Coleman/Weedmaps

“Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.”

Among patients who used cannabis as a direct strategy to manage their lupus symptoms, 83% said they would recommend it to another person with lupus. Yet 96% of respondents reported that their doctors had not talked with them about using cannabis to treat lupus, which indicates that most people are seeking out medical marijuana on their own.