Dr Frankel talks about his personal experience with gout and treating it with CBD. Many people are turning to CBD products to relieve gout pain due to its anti-inflammatory and analgesic effects. A few studies have explored the use of CBD for gout; here’s what they’ve found out. Does CBD Work for Gout? CBD may be an effective treatment for gout pain. This form of arthritis is incurable but manageable.
GOUT PREVENTION AND TREATMENT WITH CANNABIDIOL
Just about five years ago, as I was enjoying some leisure time relaxing and reading a book, I suddenly felt some tingling in the big toe of my left foot. Naturally, I attributed it to a new pair of shoes I had recently purchased which were a bit tight. However, within a few hours, I was in a considerable amount of pain, so I began noting the swelling and erythema (redness) around that area.
It wasn’t long before I was certain that I was experiencing my first episode of Gout. The symptoms? It was unusually painful. Walking, and even working, were challenging. Sleeping was very difficult as well, as the pain awakened me if the sheets merely grazed my toe.
Being a trained physician, you’d think I would seek medical advice. Did I?
Of course not! Doctors rarely properly care for themselves. Like most people, I took over-the-counter anti-inflammatory tablets (think: “Advil”) and several days later the pain and swelling subsided. Within a week I was fine… enough.
The Road Less Traveled
What if I had chosen the conventional medical route? Since uric acid is drawn from the blood into the joint during an attack, it often reads low anyway, so I never actually bothered checking my uric acid levels. I had no interest in starting medically prescribed Allopurinol to lower my uric acid.
For about one year I was just reactive, so I relied on NSAIDs every time I had an attack, which commonly occurred every 3-4 months.
Over time, as I continued to learn more about the benefits of CBD, it came to mind that the daily doses of Whole Plant CBD that I had been taking for my overall health and well-being may very well have been a potential preventive therapy for gout. Given the potential health costs of long term overuse of NSAIDs, Whole Plant CBD seemed like a great alternative.
By the end of that first year, unbeknownst to me, I had experienced my last episode! It has been about four years since my last flare-up, and even the tiny amount of swelling that remained after my first episode has resolved. Gout… GONE.
Cannabis as a Therapeutic Alternative
Over the past four years or so I have seen several patients with gout, and I have recommended a combination of both systemic CBD for prevention, along with a transdermal CBD/THC formulation for acute attacks. With attention to symptoms, the preventive CBD alone may be all we’ll need to stay one step ahead.
There are currently about 8 million patients afflicted with gout in the United States, which is clearly a significant number, so further studies are certainly needed to determine the best and most effective Cannabis treatments for this condition.
Let’s give CBD a chance.
Let’s advocate for more research.
Allan Frankel, MD Dr Allan Frankel is one of the few physicians in the US who truly understands Cannabis as a medicine. All treatments suggested have been well studied. Every patient seen by Dr Frankel is given a personally created Treatment Plan created with the patient’s specific issues defined. Plant medicine requires “tuning” of the dosing. Dr Frankel works with his patients thru a messaging portal. The use of this portal, allows quick and simple follow up contact with Dr Frankel. Patients are not charged for these messages, as this is how Dr Frankel has learned what he has learned. Follow up appointments in person or by phone/video are also available when needed
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CBD Oil for Gout: Does Cannabis Oil Help with Gout Relief?
Gout is a common yet unusually uncomfortable form of arthritis. It results from the inflammation caused by the crystallization of excess uric acids that accumulate in the joints. As a result, the joints become inflamed, red, and tender, causing disturbing pain in the feet.
The condition may be caused by a few different factors, but researchers believe the Western diet is the major one to blame. Foods high in uric acid and low in essential nutrients, such as hydrogenated fat, sugar, and alcohol may speed up the development of gout.
The aforementioned inflammation and pain seem to respond well to cannabis compounds. In particular, CBD (cannabidiol) has demonstrated effectiveness in curbing inflammatory pain.
Is CBD a viable tool for treating gout?
How much CBD is enough to relieve the gout pain?
Continue reading to find out.
Gout 101: What You Need to Know About the “Disease of Kings”
As mentioned at the beginning of the article, gout is a type of inflammatory arthritis. It commonly affects the big toe and can be a source of chronic pain. Gout develops due to deposits of uric acid crystals in the joints, which are sharp and can cause excruciating pain when jostled.
The uric acid forms naturally from the breakdown of purines. When you consume too many purine-rich products, your body will produce more uric acid than it can excrete, and its concentrations will become too high.
90% of gout cases occur when the kidney cannot get rid of uric acid properly.
Gout is often referred to as the ‘disease of kings,’ as kings were known for consuming rich food and drinks. Today, the disease has become more common because standard American diets include high-purine products.
Other risk factors of gout include:
- Being male
- Kidney disease
- History of gout in the family
- Medications such as diuretics for hypertension
- Recent trauma to a joint
- Recent surgery
People with gout experience the following symptoms:
- Pain at the base of the big toe (it gets worse with movement)
- Red, swollen, warm joint
In most cases, doctors use medications for pain management as the first-choice treatment. These medications include analgesics such as Ibuprofen or Naproxen. In more severe cases of the gut, corticosteroids are also prescribed to lower inflammation. However, conventional painkillers entail side effects like addiction, liver damage, and heartburn on top of other unwanted reactions.
For this reason, people have started exploring natural remedies for gout relief, including CBD oil.
In the next section, we cover everything there is to know about using CBD for gout. We’ll explain the science behind CBD’s health benefits, how to use CBD to get the most out of your gut treatment, and whether or not experts recommend this form of therapy.
Does CBD Help with Gout?
The Chinese and other civilizations have used cannabis for centuries to treat joint pain and gout. Ancient pharmacopeias mention the anti-inflammatory and painkilling properties of the herb, touting it for the lack of unpleasant side effects.
Although modern research on CBD and gout is in an early stage, some studies have suggested that cannabis may be an effective remedy for joint pain and inflammation associated with the condition. Similar to our ancestors, modern researchers also underlines the lack of unwanted reactions from such treatment.
CBD is a phytocannabinoid (Phyto = from plants) that interacts with the human endocannabinoid system (ECS) — the master regulatory network that helps the body maintain a balance between all organ systems and their functions.
The ECS regulates mood, memory, emotional processing, cognition, sleep, body temperature, fertility, immune response, pain, and more.
Whenever any of these functions gets compromised, the ECS starts to release its endocannabinoids (endo = from within) that bind to cannabinoid receptors and help the body regain its natural balance.
When you take CBD, it signals the ECS to produce more endocannabinoids than usual and slows down their breakdown; with more cannabinoids circulating in the body, the ECS can efficiently restore homeostasis, keeping you healthy.
The interaction between CBD and the ECS results in anti-inflammatory effects and alteration of pain signals.
On top of that, CBD has 65 molecular targets, which explains its therapeutic versatility.
Let’s take a look at what scientists are saying about the idea of using CBD for gout.
Studies on CBD and Gout
In a 2015 study published in the European Journal of Pain, the research team investigated the effects of transdermal CBD in a rat model of arthritis. They found out that “transdermal administration of CBD has long-lasting therapeutic effects without psychoactive side effects (1). Thus, the use of topical CBD has potential as an effective treatment of arthritic symptomatology,” as cited in the study. Although these results were noticed in rats, they are encouraging for gout patients seeking relief from pain and inflammation, as all animals have the same endocannabinoid system.
According to a 2018 review of the literature published in Current Opinion in Pharmacology, cannabinoids such as CBD and THC could potentially treat pain linked to osteoarthritis, the most common form of arthritis that causes the cartilage and bones to degrade. The authors of the report also noted that the body’s ECS has an important role in pain signaling from joints to the brain. This could benefit patients who experience high levels of pain from gout (2).
Another 2018 study conducted by Baron et al. reported positive results from a cohort of medical cannabis patients. Researchers found that cannabis strains high in caryophyllene and myrcene — one of the many terpenes in the plant — were successful in treating headaches, migraines, and other sources of pain, including arthritis (3).
While it’s true that no study has yet investigated the effects of CBD specifically on gout, the condition stems from arthritis, so the above studies may serve as a decent point of reference.
What Experts Are Saying About Using CBD for Gout
According to Dr. Jason McDougall, a professor in the department of pharmacology and anesthesia at Dalhousie University in Halifax, Nova Scotia, cannabinoids could be able to manage general arthritis pain.
In his interview with Canadian Broadcasting Corp. (CBC) Radio, McDougal talks about the nerve endings of arthritis sufferers and how cannabis may help improve their functioning:
“They’re all bare, they’re all raw and responsible for feeling a lot of pain. What we hypothesize is that by locally administering these cannabis-like molecules to those nerves, we’d actually be able to repair them and reduce the pain of arthritis.”
Another chronic pain expert, De. Daniel Clauw, who is a professor at the University of Michigan in Ann Arbor, shares his tips for using CBD oil alone to treat different types of arthritis. In an interview with Arthritis.org, Clauw says, “It appears as though it is very safe. The treatment includes low doses of CBD in 5 to 10 milligrams twice daily and progressing to higher doses of 50 to 100 milligrams per day if necessary. If symptoms persist, patients may try a CBD product that contains a small amount of THC.”
Holistic healthcare practitioner Debra Rose Wilson, Ph.D., has also supported the benefits of treating gout with CBD. Wilson presented her opinion in Medical News Today:
“At a time when we are trying to reduce the use of pain relievers, CBD oil can be an effective approach to managing the pain of arthritis. Researchers have also recognized the role that CBD could play in reducing the pain-causing inflammation of arthritis.”
How to Use CBD for Gout
At this point, you’re probably wondering how to use CBD for gout and reap the greatest benefits. You can target the condition from two angles by using CBD topically or by taking an oral form.
Here’s how both methods work.
Use CBD Topically for Gout
Topical products are formulated to help the user deal with localized problems. For gout victims, this means relief from their flare-ups as well as overall improvements in inflammation and pain. Clinical trials and scientific publications in recent years have proven what people have already known for centuries: that cannabis is a remarkably potent anti-inflammatory.
When you apply CBD to the skin — by rubbing a cream or salve into it — the cannabinoid interacts with the CB2 receptors located in the skin’s epidermis layer. This interaction triggers anti-inflammatory responses that reduce the redness and swelling of gout, as well as the pain that comes with it. The absorption rate will depend on the product’s formula, but the first effects should show up within 30–60 minutes after use.
When searching for the best CBD topicals for inflammatory arthritis, make sure to look for products that contain only natural ingredients and have been tested for potency and purity by a third-party laboratory.
Use CBD Orally for Gout
It’s worth noting that studies have shown CBD oil to be most potent and effective when taken as a “full-spectrum” extract under the tongue. The full-spectrum means that the product is made using the entire plant, and as such, it contains all naturally occurring phytonutrients from hemp. This includes cannabinoids, terpenes, flavonoids, vitamins, minerals, and essential fatty acids. These compounds help the body to process CBD more efficiently, allowing lower doses to remain effective. Full-spectrum products are still non-psychoactive, as they only contain 0.3% THC or less, which isn’t enough to get the user high.
To take CBD orally for gout, you’ll need to squeeze up the desired amount of CBD using the dropper attached to your bottle of CBD oil, place it under your tongue, and hold it there for up to 60 seconds before swallowing. From there, the oil will absorb through the tiny blood vessels in your mouth, avoiding the liver and the first-pass metabolism. As a result, the first effects usually show up within 15–30 minutes after ingestion, compared to capsules and edibles, which may need anywhere between 40–90 minutes to kick in.
CBD Oil and Allopurinol: Which Is Better for Gout?
CBD is known to interact with many prescription medications. CBD inhibits the activity of the cytochrome p450 system, which is a group of enzymes that metabolizes active ingredients in drugs. When you take CBD alongside some medications, it may cause a subtherapeutic effect or lead to the toxicity of those active ingredients depending on what type of interaction occurs.
Allopurinol, which is the most commonly prescribed pharmaceutical to increase the excretion of uric acid, happens to use the cytochrome p450 system, so there’s a risk of CBD-drug interactions. In this case, CBD decreases allopurinol’s activity, resulting in the aforementioned subtherapeutic effect.
If you want to avoid potential CBD-drug interactions, we encourage you to visit a doctor experienced in cannabis therapies. A qualified physician should also be able to point you in the right direction when it comes to determining the right CBD dosage for gout.
Speaking of which…
CBD Oil Dosage for Gout
Finding the right amount of CBD for your individual situation may be challenging, as there’s no one-size-fits-all dosage for specific conditions. Everybody is different, and so will be their response to different doses of CBD. What works for one person may not necessarily work for you; some people benefit from doses as small as 10–15 mg daily, whereas for others, the optimal dosage ranges between 50–100 mg.
The optimal amount of CBD for each individual depends on factors such as age, gender, weight, diet, metabolism, physical activity, the severity of pain, and previous history with CBD products.
The best approach to dosing CBD for gout is to start low (say 5–10 mg daily) and gradually increase the dosage until you reach the amount that provides the desired relief. If you don’t notice any changes in your symptoms after a week, you may add another 5-10 mg to your dosage and test it out for another week. Once you’ve found an effective dose, you can stick to it, as people don’t build a tolerance to CBD.
Similar rules apply to using CBD topically for gout. When you apply a CBD cream for the first time, wait for up to 1 hour and evaluate the effects. If you don’t get relief from your gout pain, you can rub another dose of the cream into the affected area.
Is CBD Safe for Gout?
CBD has a well-established safety profile. Numerous health agencies, such as the World Health Organization (WHO) have acknowledged CBD as a safe and well-tolerated compound. According to the studies that have tested the safety and efficacy of CBD, humans can tolerate doses of 1,500 mg daily for several weeks without dangerous side effects.
That being said, CBD has a few adverse reactions; they are nearly non-existent when you take CBD in normal doses, but it’s important to, at least, briefly mention them.
The side effects of CBD include:
- Dry mouth
- A temporary drop in blood pressure
- Dizziness (resulting from the above)
- Changes in appetite
As mentioned, there’s also a risk of CBD-drug interactions, so if you take any medication for gout, make sure to consult a doctor before buying CBD oil.
What Other Oils Are Good for Gout?
Some people find that essential oils help complement gout treatment. If you want to enhance the efficacy of CBD for the condition, you can use the following essential oils by diluting them in a carrier oil and apply to the skin:
- Lemongrass Oil – lemongrass oil is commonly used for its moisturizing properties. Research also suggests that it provides antimicrobial and antibacterial effects (4).
- Celery Seed Oil – according to some studies, Indian celery seed oil can enhance the effects of gout medications. It boosts the anti-inflammatory effects, reducing painful swelling (5).
- Yarrow Oil Extract – this oil is extracted from a flowering plant known as achillea millefolium, or simply the common yarrow. It has been used for centuries to treat arthritis, indigestion, and wounds. Modern research points to yarrow oil extract as a potent anti-inflammatory (6).
- Olive Leaf Extract – Mediterranean folks used olive leaf extracts as a remedy for gout for hundreds of years. According to clinical studies, olive leaf is effective in reducing gout symptoms such as inflammation and pain. It may also prevent gout attacks due to its powerful antioxidant properties (7).
- Biota Orientalis Extract – this oil comes from a Chinese cypress tree and has been used in traditional Chinese folk medicine for the prevention and treatment of gout. Some studies suggest that it may help reduce uric acid levels (8).
- Ginger Extract – ginger is used around the world as both a spice and a medicine. Researchers believe that ginger has antioxidant, anti-inflammatory, and anti-gout properties. Ginger extracts may be able to reduce uric acid levels to stop future gout flare-ups (9).
How to Prevent Gout
Most people can avoid gout by introducing simple changes to their lifestyle. Dietary changes that can decrease your risk of developing gout include cutting out high-purine foods, such as high-sugar processed food, alcohol, and trans fats. Also, increasing the intake of antioxidant-rich foods such as vegetables or grass-fed meat may help prevent the condition. Doctors recommend limiting alcohols and drinks sweetened with fructose on top of increasing water intake to help the kidneys flush out the excess uric acid.
Some people are at a higher risk of developing gout, especially those with a family history of gout attacks or an underlying health issue such as kidney underperformance. In these cases, doctors may prescribe medications that decrease the concentrations of uric acid in the blood, such as Allopurinol.
Final Verdict: Is CBD Oil a Viable Option for Gout?
Gout is a type of arthritis that triggers unusually painful inflammation in the joints, which can deteriorate upon engaging in simple activities, such as walking. There are certain dietary mistakes, such as the consumption of large amounts of processed food or fructose, which may spur the onset of gout. Genetics, kidney health, and comorbid conditions are also common risk factors.
Because many conventional medications for gout come with side effects and risks, people are seeking out natural alternatives, such as CBD oil, to manage their symptoms.
Current research suggests that cannabinoids in CBD oil are remarkable anti-inflammatory agents and pain relievers that can treat different types of arthritis, such as osteoarthritis or rheumatoid arthritis. Although the studies into the benefits of CBD for gout are in their infancy, current findings are promising and warrant future investigation.
There is no such thing as “the best form of CBD for gout” or the best dosage. Everybody is different, so determining the right product type and potency depends on a range of individual factors, such as your weight, metabolism, the severity of pain, and more.
Regardless of the product type, you decide to include in your routine, always consult your physician before beginning any new treatment for gout. Doing so will help you avoid potential CBD-drug interactions.
- Hammell, D C et al. “Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.” European journal of pain (London, England) vol. 20,6 (2016): 936-48. doi:10.1002/ejp.818
- O’Brien, Melissa, and Jason J McDougall. “Cannabis and joints: scientific evidence for the alleviation of osteoarthritis pain by cannabinoids.” Current opinion in pharmacology vol. 40 (2018): 104-109. doi:10.1016/j.coph.2018.03.012
- Baron, Eric P et al. “Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort.” The journal of headache and painvol. 19,1 37. 24 May. 2018, doi:10.1186/s10194-018-0862-2
- Shah, Gagan et al. “Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass).” Journal of advanced pharmaceutical technology & research vol. 2,1 (2011): 3-8. doi:10.4103/2231-4040.79796
- Whitehouse, M W, and D E Butters. “Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products.” Inflammopharmacology vol. 11,4 (2003): 453-64. doi:10.1163/156856003322699636
- Tadić, Vanja et al. “The estimation of the traditionally used yarrow (Achillea millefolium L. Asteraceae) oil extracts with anti-inflammatory potential in topical application.” Journal of ethnopharmacology vol. 199 (2017): 138-148. doi:10.1016/j.jep.2017.02.002
- Flemmig, J et al. “Olea europaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase.” Phytomedicine : international journal of phytotherapy and phytopharmacology vol. 18,7 (2011): 561-6. doi:10.1016/j.phymed.2010.10.021
- Zhu, Ji Xiao et al. “Effects of Biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver.” Journal of ethnopharmacology vol. 93,1 (2004): 133-40. doi:10.1016/j.jep.2004.03.037
- Mashhadi, Nafiseh Shokri et al. “Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence.” International journal of preventive medicine vol. 4,Suppl 1 (2013): S36-42.
Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.
CBD for Gout – August 2022
According to the John Hopkins Arthritis Center, several drugs can be used to treat gout flare-ups (5 ) . These include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen and naproxen
While the medications mentioned previously are effective, doctors often prescribe higher dosages to manage an acute attack of gout. These changes could cause side effects, which may be harmful to some people.
Mayo Clinic says side effects from using NSAIDs include high risks of developing stomach pain, bleeding, and ulcers (6 ) . Meanwhile, colchicine use can result in vomiting, nausea, and diarrhea.
The use of corticosteroids can lead to sudden mood changes, high blood pressure , and increased blood sugar levels (7 ) . Corticosteroids are often prescribed to patients who cannot take NSAIDs and colchicine .
Gout is an incurable type of arthritis that affects joints, particularly the big toe joint. However, with medications and self-management, it can be treated (8 ) .
To avoid the side effects of gout medications, more patients are turning to cannabidiol (CBD). It has been shown to have analgesic (pain-relieving) and anti-inflammatory properties that may be beneficial to gout patients.
CBD comes from the Cannabis Sativa plant. Unlike tetrahydrocannabinol (THC), it is non-psychoactive.
THC is the other primary ingredient of medical marijuana and also comes from the Cannabis Sativa plant. Like CBD, THC can be used medicinally.
However, THC is often used recreationally and sometimes abused (9 ) . Because of THC’s addictive nature, it is likely that users may develop a dependence on it.
How CBD Oil Works to Alleviate Symptoms of Gout
Findings from the Centers for Disease Control and Prevention (CDC) report that gout is caused by hyperuricemia, the excessive uric acid buildup in the body (10 ) .
Individuals who have increased chances of developing hyperuricemia are usually obese males who have health problems, like hypertension, diabetes, and reduced kidney function (11 ) .
Certain diets may increase the likelihood of people developing gout. These consumption behaviors include drinking large quantities of alcohol and fructose-rich beverages.
Also at risk are those who often eat food high in purines, which the body breaks down into uric acid. Such foods include organ meats, red meats, and seafood, like sardines, tuna, and anchovies.
Gout has been dubbed as the “disease of kings” because it is generally caused by overindulgence in food and drinks (12 ) .
In the affected joints, gout may be detected when the following symptoms are observed: intense pain, redness, swelling, and heat (13 ) .
Gout may come in the form of acute gout or chronic gout. Acute gout only affects one joint, while chronic gout may occur repeatedly and affect more than one joint (14 ) .
CBD for Inflammation
Further research needs to be done on CBD’s therapeutic effects on gout symptoms. However, a significant number of studies conducted on CBD have suggested its anti-inflammatory properties.
A study published in Future Medicinal Chemistry concludes that cannabinoids have anti-inflammatory effects that may help treat several types of arthritis and inflammation-related diseases (15 ) . The primary cannabinoids are CBD and THC.
Cannabinoids are compounds that may come from the body, from plants, or laboratories. They interact with the endocannabinoid system (ECS) and activate cannabinoid receptors , known as CB1 and CB2 receptors.
Cannabinoids help the ECS with several functions, like immune responses, mood, appetite, and memory.
Cannabinoids have been shown to help suppress cytokines at inflammatory sites in the body, reducing symptoms of inflammatory diseases (16 ) .
Cytokines are a group of proteins that can be classified as pro-inflammatory or anti-inflammatory (17 ) . Their modulation can balance the initiation and resolution of inflammation (18 ) .
CBD is a cannabinoid that is known to have anti-inflammatory properties (19 ) .
Another study in 2019 has found that CBD has anti-inflammatory and antioxidant properties. These therapeutic benefits may help treat several conditions, like arthritis, diabetes, cardiovascular diseases, psychosis, among others (20 ) .
CBD for Pain Relief
A 2018 study states that cannabinoids, like CBD, may be useful in treating inflammation and pain (21 ) .
Research conducted in rodents that have osteoarthritis showed that CBD reduced inflammation and blocked osteoarthritis pain signals (22 ) .
The study suggested that CBD might be a safe and effective therapy for osteoarthritis. The researchers believe that they have discovered CBD’s neuroprotective properties.
Another study, this time on CBD as a topical pain reliever, has shown that the use of CBD gel on rat models markedly attenuated joint swelling and pain, without causing psychoactive side effects in the test subjects (23 ) .
In the study, the application of 6.2 mg and 62 mg of CBD gel per day, for four consecutive days after arthritis pain began, helped treat arthritis in rats .
The results of the animal study showed CBD as a promising treatment for pain relief in humans.
The Pros and Cons of CBD Oil for Gout
- Animal and human studies have reported the benefits of CBD in treating symptoms of gout.
- CBD is safe for use because it has an excellent safety profile (24 ) .
- CBD is non-addictive (25 ) . Thus, gout patients may not have to worry about developing a dependence on it.
- While there are studies on CBD’s potential in alleviating gout symptoms, research on CBD’s effectiveness in treating gout itself is lacking.
- The United States Food and Drug Administration (US FDA) has not approved CBD use aside from the treatment of epilepsy.
- There is no standard dosage for CBD when used for the treatment of gout.
- CBD products are unregulated, resulting in a proliferation of mislabeled CBD products online (26 ) .
How CBD Oil Compares to Alternative Treatments for Gout
Although gout cannot be cured completely, patients’ lifestyle changes help manage their symptoms. These modifications include weight loss, diet changes, hypertension control, and change in medication regimens (27 ) .
A study has found that cherry consumption helps lower the risk of gout attacks (28 ) .
Studies have also been made on whether vitamin C intake helps in the attenuation of gout. However, the results of these studies are conflicting.
A study reports that vitamin C reduces uric acid levels and prevents gout recurrences (29 ) . Another study, meanwhile, concludes that vitamin C reduces the risk of gout development but does not significantly reduce uric acid in gout patients (30 ) .
Meanwhile, th e use of CBD has minimal risk factors, as common side effects include tiredness, diarrhea, and changes in appetite or weight (31 ) . CBD use may also help complement the alternative treatments mentioned previously.
However, it is not recommended to use CBD alongside traditional gout medications, such as corticosteroids (32 ) . The liver enzyme cytochrome P450 metabolizes these medications.
CBD may inhibit the P450 enzyme system and increase the risk of amplifying the side effects of gout medications (33 ) .
How to Choose the Right CBD for Gout
There are three types of CBD oils : full-spectrum CBD oil, broad-spectrum CBD oil, and isolates.
Full-spectrum oils make use of all the ingredients of cannabis plants, including less than 0.30% THC, fatty acids, flavonoids, terpenes, and essential oils.
The main advantage of using a full-spectrum oil is that its active ingredients synergize to produce an entourage effect. This mechanism is believed to generate maximum therapeutic benefits from the ingredients of the cannabis plant.
Full-spectrum oils contain THC, which may be detected via drug tests. THC may also cause mild psychoactive effects in some individuals.
Gout patients who want to avoid these potential risks may choose to buy broad-spectrum CBD oil. This type of oil has all the ingredients of a full-spectrum oil sans the THC.
Those who are looking for a CBD oil made of pure cannabidiol may purchase CBD isolates.
CBD Dosage for Gout
The rule when using CBD for gout is to begin with a low dosage. Patients can start with a few milligrams of CBD and increase the dosage in small increments if no adverse effects are observed.
The dosage amounts may be increased until significant improvements are noted .
Body weight should be considered when choosing a CBD dosage. The heavier the patient, the larger their required dose.
Average adults can take a maximum of around 5 mg of CBD daily.
Before adding CBD to one’s gout medication regimen, always consult with a doctor first.
How to Take CBD for Gout
There are various ways to take CBD in the treatment of gout. One way is through ingestion via CBD oil, CBD tinctures (droppers), CBD pills, CBD gummies , or CBD gel caps.
When a CBD product goes through the digestive tract, it takes effect in one to two hours. When taken sublingually (under the tongue) through tinctures, CBD may take effect in 15 to 45 minutes.
CBD can also be applied topically , on body parts affected by gout, as it is available in lotion, salve, or balm format.
There are CBD oil massages available, which may be beneficial to gout patients. CBD oil may help alleviate pain associated with gout (34 ) .
Another format is CBD vape or pen. When CBD is inhaled, effects may be observed instantaneously.
However, taking CBD by vaping is not recommended. There have been incidents that suggest that vaping may cause lung problems (35 ) .
Medical cannabis-related products, like CBD, may help in the treatment of gout symptoms. Further research, however, needs to be made on the therapeutic effects of CBD on gout itself.
Compared to most gout medications, CBD has been shown to have a more favorable safety profile. It is a treatment worth exploring as an added therapy for gout relief.