CBD Oil Absorption

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Bioavailability refers to the degree and rate at which a substance is absorbed into your bloodstream. Read more on how dosage and consumption method can affect how much cannabis your body uses. How much CBD is actually absorbed by your body? Here are the best ways to increase CBD absorption to get the biggest bang for your buck. Getting the most out of your CBD is essential for a variety of reasons. The first being it is expensive. Buying CBD oil can cost upwards of 100 dollars for a 30ml bottle. If you are using CBD daily (which we highly recommend), this becomes a monthly expense. Another reason is you want as much CBD […]

Most THC and CBD oil goes to waste in your body—here’s why

If you knew that only 6% of your CBD gummies would enter your bloodstream to do their job, would you still purchase them? Amid the current frenzy surrounding cannabis and its therapeutic benefits, it’s easy to gloss over the bioavailability of cannabis products.

Bioavailability refers to the degree and rate at which a substance is absorbed into your bloodstream to be used where needed. Physiological processes and consumption methods can affect cannabis absorption, rendering its effects somewhat hit-and-miss.

It’s critical to get clued up about bioavailability in order to maximize the medicinal potency of cannabis. The more bioavailable your cannabis, the lower the quantity of the plant you need to reap its benefits.

What factors influence cannabis bioavailability?

The surge in cannabis popularity can be partly attributed to the range of consumption methods available. Edibles and tinctures can have less of the stigma traditionally associated with joints. However, when cannabinoids such as CBD and THC are ingested in oil form—oil is also used to make edibles—their bioavailability becomes compromised.

CBD and THC oils resist absorption into the bloodstream because the human body is up to 60% water . Basic science—and salad dressing—dictates that oil and water do not mix, and the same is true for cannabis oil and the human body.

“Cannabinoids are fat-loving molecules and have to traverse a cellular environment that is aqueous or watery,” explains Dr. Patricia Frye, a member of the Society of Cannabis Clinicians and chief medical officer at Hello MD . When cannabis is consumed as an oil, the onset of effects can become delayed and bioavailability limited.

Another phenomenon that limits oil-based cannabis extracts from reaching the bloodstream is the first-pass effect. When cannabis is ingested orally, it is absorbed in the gastrointestinal tract and transported via the portal vein to the liver, where it is metabolized. As a result of this process, only a limited quantity reaches the circulatory system. Since cannabis oil is often taken orally, its efficacy can be hindered.

Are some cannabinoids more bioavailable than others?

There has been some investigation into CBD, THC, and less into cannabinol, or CBN. Studies have shown that the bioavailability of cannabinoids depends on the method of delivery.

When applied as a topical ointment or transdermal patch, CBD can penetrate the tissue ten times more effectively than THC. The same is true of CBN.

THC, however, is more bioavailable than CBD when administered orally or delivered via the lungs. A clinical study found that concentrations of THC in the bloodstream appeared 30-50% higher than CBD following oral delivery as a sublingual spray.

However, the bioavailability of THC is still limited when consumed orally, averaging only 4-12%. When smoked or vaped, the bioavailability of THC leaps to an average of 30%.

Which methods of cannabis consumption optimize bioavailability?

Some of the most common and convenient cannabis products, such as capsules, soft gels, tinctures, and edibles, limit bioavailability due to the first pass through the liver. “With edibles, absorption is slow, unpredictable, and highly variable,” says Frye. “Only about 6% of the dose is absorbed. The onset of action can be as long as 6 hours; it’s very easy to take too much, and the effects can last as long as 20 hours!”

Oral administration lasts longer than smoking, eliminating the need for frequent dosing. Oral methods also avoid irritation to the airways and the risk of malignancies associated with smoking or vaping.

That said, inhaling cannabis guarantees increased bioavailability because molecules are transported by vapor particles directly to the alveoli in the lungs. This allows cannabinoids to rapidly enter the bloodstream without being metabolized by the liver.

Another lesser known method of administration is intranasal delivery, which enables cannabinoids to be easily absorbed with a rapid onset of 10 minutes or less. “Intranasal methods are highly bioavailable at 34-46%,” says Frye. “It’s a particularly helpful mode of delivery for patients who are having a seizure or for patients trying to abort an impending seizure or migraine.”

Transdermal patches can be super effective at targeting localized or systemic pain. They allow for a steady infusion of active ingredients to the delivery site, so the patient is unlikely to experience spikes of THC in the bloodstream.

Finally, nano-emulsions and micro-emulsions can dramatically increase the stability and bioavailability of cannabinoids. These novel formulations use nanotechnology to offer up to 100% bioavailability. Frye cautions, however, that the research is still scarce. “We don’t know the full extent of how these manipulations affect cannabinoid activity at the cellular level,” she says.

What tips or tricks can help increase bioavailability?

One method that boosts the absorption of edibles is to combine cannabis product with fats. Frye recommends combining edibles or tinctures with healthy fats such as guacamole, hummus, or dark chocolate. If you’re feeling less virtuous, however, ice cream works as a treat. The same goes for alcohol-based tinctures.

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For those who smoke or vape, bioavailability can be enhanced by minimizing sidestream loss and increasing the number of puffs. “Using a desktop or handheld vaporizer with flower will eliminate sidestream losses,” Frye advises. If you think you get more bang for your buck by holding your breath, think again. “There is no evidence supporting holding one’s breath for more than 10 secs,” says Frye.

Some final words of advice from Dr. Fyre, for those looking to optimize cannabis bioavailability: “The most cost-effective way to use cannabis is not to use more than you need. Less is more,” she says. Due to its biphasic nature, excessive dosing may exacerbate the symptoms you’re trying to alleviate.

your Guide To Increase CBD Absorption – Luce Farm Wellness

As simple as CBD may seem, there’s some distinctive science behind the inner-workings of the cannabinoid that can maximize its results. While we know what CBD is capable of once it’s absorbed – it’s how much is actually absorbed that could affect your experience overall. Not to mention, actual CBD absorption will affect how much you use and how much you spend on your all-natural health and wellness routines.

That means, it’s crucial for everyday consumers to understand the best CBD routes of administration for bioavailability, and the best CBD absorption methods and tips. But don’t worry – as complicated as it might sound, we’ll break it all down in an easy-to-understand manner (that even includes adding chocolate to your CBD routines!).

So, without further ado – let’s address how to increase CBD absorption to get the biggest bang for your buck.

What Is CBD Bioavailability?

Before we learn how to increase CBD absorption let’s first better understand the bioavailability of CBD. Bioavailability is a term that references the percentage of any medication that’s actually absorbed into the bloodstream. Meaning, when you ingest any form of medication, herb, or supplement, although the dose may contain 50mg, far less is actually absorbed. That means there’s lots of room for improvement when it comes to your body making full use of your CBD dose.

CBD absorption rates depend on a couple different factors. One being, the type of product you’re consuming. For instance, edibles or CBD products you swallow will have a lower CBD absorption rate in comparison to the sublingual method. Why? Because your body metabolizes CBD through the digestive system which is chock-full of enzymes and acids that can degrade and deteriorate the cannabinoid’s delicate structure.

In comparison, CBD oil sublingual bioavailability is much higher. When you hold CBD oil under your tongue for 30-60 seconds, the compounds are absorbed directly into the bloodstream through the sublingual artery. Meaning, there’s less time and probability for your body’s natural enzymes and compounds to break down and reduce the amount of CBD actually absorbed.

The second factor that’ll affect CBD oil bioavailability specifically is the type of carrier oil that’s used. Because our bodies are made of 60% water the best CBD absorption rates come from water-soluble product types. Hence, why Medium-chain triglycerides or MCT oil is one of the best ways to absorb CBD. MCT has a lighter molecular weight than other carriers and is soluble in water which allows for maximum CBD absorption when combined.

Of course, just like some medications or vitamins are recommended only after a meal – there are some steps you can take to maximize your CBD absorption rates. So, next we’ll cover the best ways to absorb CBD with a few tips and tricks.

Top 4 Ways to Maximize CBD Absorption

Put simply – when you maximize your CBD absorption, you maximize the efficacy of its benefits. So, if you’re looking to get the most out of each dose here are 4 simple ways you can increase CBD absorption.

Consume with fatty snacks

The smaller the molecule, the better it will be absorbed by the body. That’s the simple principle behind the method of consuming CBD with snacks, or meals high in fat. CBD’s molecule structure is highly soluble into fats, and fatty oils are successful at dissolving large CBD compounds into smaller sizes. Another reason why MCT oil is so popular, is it’s a “smaller” fat than most others you’d digest, and easier to absorb too.

When you combine CBD with the following fatty foods and snacks, the fat helps CBD molecules stay in-tact and allows more to be absorbed.

  • Dark Chocolate – Nearly 65% of dark chocolate’s calories are fat, and the rich treat is chock-full of antioxidants for extra benefits, too.
  • Fatty fish – Salmon, mackerel, trout or herring and other fatty fish help preserve CBD molecules, with the help of its omega-3 fatty acids, protein levels, and nutrients.
  • Avocados – One of the most popular ‘healthy fats’, adding an avocado to your CBD routine can maximize bioavailability.
  • Nuts – A handful of fatty nuts like almonds, and walnuts can work wonders for increasing CBD absorption, especially on the go.
  • Eggs – Consume your CBD every morning? Add a side of eggs that contain healthy fats, vitamins, protein, and nutrients to increase CBD’s bioavailability.
  • Cheese – Packed with healthy fats, cheese is another ideal pairing to maximize CBD absorption.
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Supplement with herbs

Similar to foods, certain herbs can also increase the bioavailability of CBD. So, if you’re interested in increasing your personal CBD absorption rate, consider adding the following herbal compounds to your CBD routine.

  • Piperine – Piperine is an alkaloid that’s primarily found in black pepper. It has the ability to enhance CBD’s bioavailability metabolic effects of the liver by inhibiting the liver’s metabolic effects.
  • Turmeric – Turmeric also contains piperine and improves bioavailability similarly to pepper. However, turmeric also contains the curcumin which helps magnify the effects of both. Recent studies prove that piperine enhances the absorption of curcumin. So all in all, when consuming piperine, turmeric and CBD together – the compounds all have greater absorption than when consumed alone.
  • Apigenin – Apigenin is a compound that’s found in abundance in chamomile flowers, but also other consumables like oregano, parsley, celery, and dark chocolate (bonus!). It has the power to prevent CBD from breaking down, by binding to enzymes and strengthening its overall bioavailability.
  • Capsaicin – Primarily found in spicy, hot, peppers, Capsaicin shares a similar molecular structure to CBD which helps its efficacy for increasing its bioavailability. Early studies prove that the compound has the ability to enhance cannabinoid’s responses including CBD, CBG, and THC.
Seek out CBD chock-full of terpenes

Terpenes may be well-known as the aromatic centers of hemp and cannabis plants, but in actuality are so much more. As a quick refresher, terpenes are compounds found in the essential oils of plants and produce their signature scents. But emerging research is showing that terpenes are also capable of producing their own effects, similar to that of cannabinoids.

Even more, when combined – terpenes and cannabinoids create what’s known and proven as “the entourage effect”. Like piperine and curcumin enhancing one another’s bioavailability and effects, terpenes and cannabinoids act in the same fashion. Together, they amplify one another’s efficacy and overall strength.

That means, seeking out products that are chock-full of terpenes can increase CBD’s efficacy, like maximizing its’ absorption would too. CBD products rich in terpenes are classified as “full-spectrum”. Which means the extraction process captures the entire profile of plant cannabinoids, terpenes, and phytonutrients. In comparison to “isolate” products which references the extraction of just one cannabinoid, like CBD and no terpenes whatsoever.

Consume sublingually

Last but not least – when learning how to increase CBD absorption you must know CBD oil sublingual bioavailability is the most effective overall. Even though the tips we’ve shared will help boost CBD absorption rates no matter the consumption method – CBD sublingual bioavailability will always reign supreme.

The sublingual CBD route of administration is the most direct into the bloodstream, increasing its overall bioavailability and in turn, the CBD absorption rate, too. But still, many shy away from sublingually consuming due to the raw, pure, and all-natural flavor of some CBD oils and extracts. In that case, you can always seek out a flavored CBD oil like Peppermint to enhance the taste, experience and absorption – all in one!

High Quality CBD for Highly Effective Results

Now that you know more on the unique inner mechanisms of CBD, you can better understand how CBD consumption methods and products affect CBD absorption. As a more informed consumer, it may just be time to enhance your overall health and wellness routines for maximum efficacy and benefits.

With the information you gained today, it’s also easy to see that higher quality CBD = better results. Even more, not every CBD brand or product can be treated equally. From the type of carrier oil that’s used, to the quality of plant material and level of terpenes and cannabinoids – you now know what to look for when seeking the products with the highest efficacy.

At Luce Farm Wellness, we pride ourselves on producing the highest quality CBD for the highest level of holistic, plant-powered effects and benefits. Learn more about our hands-on approach to ensuring each batch is crafted with intention, and care, for the most effective experience available on the market today.

7 foods to elevate effects of CBD supplements

Getting the most out of your CBD is essential for a variety of reasons. The first being it is expensive. Buying CBD oil can cost upwards of 100 dollars for a 30ml bottle. If you are using CBD daily (which we highly recommend), this becomes a monthly expense. Another reason is you want as much CBD…

Getting the most out of your CBD is essential for a variety of reasons. The first being it is expensive. Buying CBD oil can cost upwards of 100 dollars for a 30ml bottle. If you are using CBD daily (which we highly recommend), this becomes a monthly expense. Another reason is you want as much CBD to get into the bloodstream as possible to experience the benefits.

Absorption and bioavailability become very important for CBD users who want to get the most out of their CBD. Research has shown that taking CBD on a full stomach increase absorption leading to high bioavailability. We have come up with seven foods to take before taking your dose of CBD to get the most out of your product.

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How to Increase CBD Bioavailability?
A study done by the University of Minnesota’s phrenological department tested bioavailability for CBD with or without food. The researchers also concluded that foods with high levels of healthy fat would also increase absorption rates.

If you are taking CBD oil, we first want to make sure you are administering it correctly. CBD oil is meant to be taken sublingually or absorbed under the tongue. Allowing CBD oil to dissolve under the mucosal glands located under the tongue fully allows the CBD to enter the bloodstream more efficiently.

Relatively speaking, CBD oil taken sublingually is the most efficient way to take CBD . Many users put CBD oil in food and will not receive the benefits of sublingual administration. If you are concerned about getting as much of your CBD to the bloodstream as possible, we recommend eating one of the foods on our list and taking the CBD oil sublingually as soon as you can right afterward.

Best Way to Absorb CBD
The foods on our list are all high in healthy fats. These foods increase the bioavailability of CBD and maximize its benefits. A recent study claims that taking CBD on a full stomach after a meal high in fat can increase the absorption rates by up to 400%.

Our seven CBD potentiators can be eaten directly before or along with your dose of CBD to maximize the effects. Experiencing the benefits of CBD can take time and consistency. Taking a regular amount along with one of these seven foods maximizes the potential to deliver the benefits.

#1 Fatty Fish
Most people agree that eating fatty fish is one of the healthiest meals available. Salmon, trout, mackerel, sardines, and herring are among the types of fish considered to contain large amounts of healthy fats.

Fish are packed with omega-3 fatty acids, protein, and nutrients but can also help you absorb CBD more efficiently. If you are experiencing mental health issues that keep you from getting everything you want to get done during the day, try eating salmon and eggs (another healthy fat) at breakfast, followed by a dose of CBD.

#2 Avocados
We didn’t feature any other fruits on our list of foods to take with CBD because they are usually made up of carbs. However, avocados are packed with fats and are the perfect food to maximize bioavailability.

Elevate the effects of CBD by eating an avocado before taking CBD sublingually. Unlike salmon, avocados are an extremely affordable way to increase absorption.

#3 Dark Chocolate
Dark chocolate is by far the tastiest and most convenient way to increase bioavailability. About 65% of the calories in dark chocolate consist of fat. Dark chocolate is also loaded with antioxidants that have some of the same benefits as CBD.

#4 Nuts
Potentiating CBD can also be done with nuts. Almonds and walnuts are among the healthiest, packed with healthy fats and plant-based protein.

Just a handful of almonds contains enough fat to increase the bioavailability of your CBD.

#5 Whole Eggs
Many people consider eggs unhealthy because of their cholesterol content; however, recent research has found that the cholesterol in eggs does not affect the cholesterol in the blood.

Eggs are, in fact, packed with healthy fats, vitamins, protein, and nutrients. They are perfect for taking with CBD if you are looking to get the most out of your CBD oil, especially if you are using CBD products to lose weight.

Taking CBD oil to lose weight is perfectly complimented with eggs because the eggs are so nutrient-dense. Taking CBD can suppress the appetite, and taken along with CBD, it can serve as a way to feel full.

#6 Cheese
Cheese is another food that is regarded as unhealthy but is actually packed with nutrients and healthy fats . A single slice of cheese can contain as much protein as a glass of milk.

Taking CBD with cheese can maximize bioavailability because it is packed with healthy fats.

#7 Coconuts and Coconut Oil
Many CBD oil manufacturers use MCT oil (coconut oil) as a carrier for their CBD. Coconuts are a great source of healthy fats and other vitamins and minerals. Cooking with coconut oil is a healthy option for butter and vegetable oil because it has fewer calories.

Taking CBD oil with MCT oil is beneficial, but eating additional coconut will deliver increased levels of absorption and bioavailability.

Enhance CBD Oil CBD oil food is a popular way of taking CBD, but we recommend eating a food high in healthy fats followed by sublingual CBD oil. Edible CBD is not as effective as CBD oil and has a much lower bioavailability.

Taking CBD on a full stomach creates the best environment for CBD to provide the most benefits possible. Utilizing our recommendation for foods with healthy fats and taking CBD sublingually will deliver the highest bioavailability and absorption rates. Next time you take CBD, try filling your stomach with some food high in healthy fats.

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