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Item no.: PU-EU993 , Content: 10 ml
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The research team used rats to investigate the role of a molecule in the brain’s hippocampus called extracellular-signal-regulated kinase (ERK), which triggers the neuropsychiatric effects of THC. The group published their findings recently in the Journal of Neuroscience through an article titled “Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus Through Bi-Directional Control of ERK1-2 Phosphorylation.”
In the study, the researchers saw that rats given THC had higher levels of activated ERK showed more anxiety behaviors and were more sensitive to fear-based learning. Rats that were given both CBD and THC acted like the control rats: they had normal levels of activated ERK, fewer anxiety behaviors, and were less sensitive to fear-based learning.
With widespread legal approval of marijuana growing, scientific research into some of the more elusive details of this drug can be explored. For instance, it has been previously shown that strains of cannabis with high levels of tetrahydrocannabinol (THC) and low levels of cannabidiol (CBD) can cause increased psychiatric effects, including paranoia, anxiety, and addictive-behaviors. Yet, why this occurs had been a mystery until now, as investigators from the University of Western Ontario, recently showed for the first time the molecular mechanisms at work that cause CBD to block the psychiatric side-effects caused by THC.
“For years we have known that strains of cannabis high in THC and low in CBD were more likely to cause psychiatric side-effects,” explained senior study investigator Steven Laviolette, PhD, a professor at Western’s Schulich School of Medicine & Dentistry. “Our findings identify for the first time the molecular mechanisms by which CBD may actually block these THC-related side-effects.”
Based on these results, the research team proposes that CBD blocks the ability of THC to overstimulate the ERK pathway in the hippocampus and thus prevent its negative side-effects.
Cannabidiol (CBD) is a trigger that binds to receptors in the human body and triggers certain reactions. Scientists and doctors around the world are quickly finding that CBD is very effective for many common diseases. CBD has positive effects in the treatment of mental disorders, sleep disorders, depression, can affect memory, motor functions, the functioning of the immune system, reproduction, pain perception, appetite and sleep.
These CBD products are safe. CBD is not psychoactive and is non-toxic to the body even in high doses.
10% EUPHORIA CBD OIL CONTAINS 1000 MG CBD IN 10 ML
INGREDIENTS: hemp oil, 10% hemp extract, Full Spectrum CBD (CBD, CBDA, CBG, CBGA, CBN, CBC) – THC IN STOCK Add to cart