With a forecasted revenue of over 20 billion by 2024, the CBD market is booming. 1 But what exactly is CBD and how effective is it? We look at 9 proven or possible health benefits of CBD oil.
In June 2018, the FDA approved Epidiolex (a plant-based formulation of CBD) to treat seizures for people 2 years of age and older with Dravet syndrome and Lennox-Gastaut syndrome (LGS), which are two rare forms of epilepsy.
Conclusion: CBD does not appear to interfere with sleep and may help people sleep better.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
Conclusion: CBD is beneficial for treating certain types of epilepsy.
Clinical Hemorheology and Microcirculation published research in 2016  that found that CBD can help ease inflammation in the pancreas  . Another paper was presented the same year in Lisbon, Portugal, that suggested that CBD could delay and protect against the development of Type 1 Diabetes.
JCJ Insight published a small study in 2017  , where researchers observed that CBD oil could help prevent blood-pressure fluctuations caused by stress. Recent research has also linked CBD with more benefits for the heart as well as the circulatory system, and the ability to lower high blood pressure.
10.1 Might Have Neuroprotective Properties
The US FDA advisors approved the prescription of Epidiolex in June 2018, a purified form of CBD for treating two severe and rare forms of epilepsy; Dravet Syndrome (DS) and Gestaut Syndrome (LGS), in patients above two years old. These two forms do not respond to anti-seizure medications.
Summary: Effective – Academic research proves that CBD can help reduce acne.
Since CBD has been studied and seen as a new drug, it is illegal to include it in food or dietary supplements or products marketed as therapeutic products. Cannabidiol is only to be included in cosmetic products, and THC contained in CBD products should be less than 0.3%  .
Cannabidiol and THC are just two of the plant’s more than 100 cannabinoids. THC is psychoactive, and CBD may or may not be, which is a matter of debate. THC can increase anxiety; it is not clear what effect CBD is having, if any, in reducing it. THC can lead to addiction and cravings; CBD is being studied to help those in recovery.
Sleep can be disrupted for many reasons, including depression. Rodents seemed to adapt better to stressful conditions and exhibited less depressive-like behavior after taking CBD, according to a review in Journal of Chemical Neuroanatomy. “Surprisingly, CBD seems to act faster than conventional antidepressants,” wrote one of the authors of a new review, Sâmia Joca, a fellow at the Aarhus Institute of Advanced Studies in Denmark and an associate professor at the University of São Paulo in Brazil, in an email interview. Of course, it’s difficult to detect depression in animals, but the studies that Ms. Joca and her colleagues reviewed suggested that in models of chronic stress exposure, the mice and rats treated with CBD were more resilient.
What are the claims?
A recent chart review of 72 psychiatric patients treated with CBD found that anxiety improved, but not sleep. “Over all, we did not find that it panned out as a useful treatment for sleep,” said Dr. Scott Shannon, assistant clinical professor of psychiatry at the University of Colorado, Denver and the lead author of the review in The Permanente Journal.
This year, 1,090 people have contacted poison control centers about CBD, according to the American Association of Poison Control Centers. Over a third are estimated to have received medical attention, and 46 were admitted into a critical care unit, possibly because of exposure to other products, or drug interactions. In addition, concern over 318 animals poured into the American Society for the Prevention of Cruelty to Animals’ Animal Poison Control Center.
“If you take pure CBD, it’s pretty safe,” said Marcel Bonn-Miller, an adjunct assistant professor at the University of Pennsylvania’s Perelman School of Medicine. Side effects in the Epidiolex trial included diarrhea, sleepiness, fatigue, weakness, rash, decreased appetite and elevated liver enzymes. Also, the safe amount to consume in a day, or at all during pregnancy, is still not known.