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cbd oil gastrointestinal

The oil may be a new way for us to feel better and receive the necessary help that our bodies need.

CBD is a powerful antioxidant and helps our immune systems.

Your Digestive System

If you have chronic inflammation, a way to see how this occurs is to look at your diet.

The Mediterranean diet is a great diet that doctors recommend. It is a diet consisting of mostly plant-based foods.

They want the benefits but are afraid of the high.

Interestingly, people who have a mutation in the gene coding for one of the endocannabinoid system components are more likely to have IBS and chronic abdominal pain – evidence that endocannabinoid dysfunction may be one of the root causes of gut disorders.

Animal studies have shown that cannabinoid stimulation of the CB1 receptor inhibited acid secretion and decreased damage and inflammation in the lining of the stomach. Preclinical research also showed that cannabinoid activation of the CB1 receptor kept the lower esophageal sphincter (the “gate” between the esophagus and stomach that works to keep stomach contents from flowing back into the esophagus) from relaxing, thereby decreasing reflux. In one human study, synthetic THC given to healthy volunteers was shown to decrease the reflux rate (although there were issues in the study since the dose was very high and caused side effects). It is clear that more research is needed to understand the role of cannabis in the treatment of GERD .

Gastroesophageal Reflux

This excerpt continues with a personal story of a young Crohn’s patient who benefited from a doctor-supervised medical cannabis regimen. Read more.

If your endocannabinoid system isn’t working properly, it may not be able to mount an appropriate response to inflammatory triggers, leading to chronic intestinal symptoms.

There are three published human studies of cannabis use for IBS , all employing synthetic THC as the study drug. Not surprisingly, one study reported all participants to have had side effects and no benefits; the study dose of 10 milligrams THC was clearly too much for the non-cannabis users who participated. The second study used lower doses, 2.5 milligrams or 5 milligrams of synthetic THC compared to placebo, and found participants with IBS diarrhea or IBS mixed type had a reduction in colonic motility, meaning THC slowed down how fast food moved through the gut. And the third study involved giving low-dose dronabinol (pharmaceutical THC ) for two days and had no effect on IBS diarrhea. As mentioned before, findings from studies using single synthetic cannabinoid compounds are difficult to translate to outcomes in patients using whole-plant preparations.