Arthritis involves the deterioration of the tissues in and around your joints. There are several types of arthritis, and symptoms include pain, stiffness and loss of motion. Arthritis treatment usually targets pain relief and improved joint function.
In one such study, researchers administered CBD to people with heroin use disorder. Over the course of a week, CBD significantly reduced heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate and salivary cortisol levels. No serious adverse effects were found.
Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects.
8. Protect Against Neurological Disease
Preclinical and clinical studies show that CBD has antioxidant and anti-inflammatory properties. Researchers deduce these characteristics can provide significant neuroprotection, or protection against numerous pathological disorders.
In a small 2018 study in the Journal of Alternative and Complementary Medicine, 11 people with post-traumatic stress disorder (PTSD) received CBD along with routine psychiatric care for eight weeks in an outpatient psychiatric clinic. Ten of the 11 experienced a decrease in their PTSD symptoms. CBD was generally well tolerated, the researchers write.
In 2018, the Food and Drug Administration (FDA) approved the use of CBD under the brand name Epidiolex to treat seizures resulting from Lennox-Gastaut syndrome and Dravet syndrome—two rare forms of epilepsy—in patients at least 2 years old.
In 2005, Canada approved the use of Sativex, an oromucosal (absorbed in the lining of the mouth) spray with equal proportions of THC and CBD, for the treatment of multiple sclerosis-related central neuropathic pain. In 2007, Canada approved the medicine’s use again for cancer pain that proved unresponsive to other medications.
Medically reviewed by Carmen Fookes, BPharm. Last updated on Nov 2, 2020.
CBD derived from hemp contains no more than 0.3% THC and is legal federally but still illegal under some state laws. Cannabis-derived CBD products, on the other hand, are illegal federally but legal under some state laws.
CBD has also been investigated for use in other forms of treatment-resistant epilepsy, usually in addition to conventional epilepsy medications. Results varied, but several trials showed CBD significantly reduced seizure frequency by almost 44% in most people. 3
Animal studies have shown some effect of CBD at relieving depression, possibly related to its strong anti-stress effect after either acute or repeated administration. 16
Conclusion: CBD may relieve anxiety before events such as public speaking but it is not known what the optimal dose is.
Growing research continues to demonstrate that CBD is an effective method of treatment for a wide range of pain-related conditions. The European Journal of Pain published in a 2016 animal study that various dosages of transdermal CBD gel (6.2 mg & 62.3 mg administered to lab rats) were effective in reducing arthritis pain and inflammation.
However, how CBD works to relieve or modulate pain is still uncertain. The psychoactive influences of CBD could distract users from the pain and help them ease the pain for just a short while.
1.1 Potential for Helping Fibromyalgia
IBS attacks are highly correlated with anxiety, and the episodes can either be triggered by dietary indiscretions like overeating or specific foods. If gastrointestinal insults like antibiotics or food poisoning are significant, the attacks may persist but only indefinitely.
Multiple Sclerosis is a chronic, autoimmune condition where the immune system eats and attacks the protective covers over the nerves in the human body. Unfortunately, there is no cure for Multiple Sclerosis.
A survey was done  on the efficacy of regulatory body-approved pharmaceutical treatments for fibromyalgia versus CBD. The prescription medicines were poorly effective compared to CBD.