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Research has shown that CBD is very low in toxicity. A study from 1981 determined the LD50 for CBD to be 212 mg per kg of body weight when given to monkeys intravenously. This suggests that humans must consume hundreds of times the average daily dose of CBD (30 mg) in a relatively short period of time to be at risk for overdosing. It is highly unlikely that anybody will ever take enough cannabidiol to induce lethal consequences.
What is CBD?
This guide covers the essential things to know about shopping for CBD vapes and CBD vape juice, plus how to use them properly. One caution: if you use prescription medications, you should always consult your doctor before incorporating CBD into your regimen.
Vaping is one of the most effective and popular ways to use CBD. With such a diverse range of products available, it’s important to know which “CBD oil” products are suitable for vaping, and how you can verify their quality.
The best way to find your dosage is to start low and then work your way up. Start with the minimal dosage, 1 to 2 mg of CBD and wait about six hours until your next dose. Gradually increase your dosage each time by 5 mg. Pay close attention to how you feel after each dose. It might not be noticeable right away, or even overnight. As soon as you experience positive effects, lock in that dosage and stick with it.
Many countries differentiate hemp from marijuana by the amount of THC produced. In the US, industrial hemp is defined as a Cannabis sativa L. plant containing no more than 0.3% THC by weight. Thanks to the Farm Bill of 2018, you can legally buy hemp flower online in nearly every state.
Contrary to popular belief, tetrahydrocannabinol (THC) and CBD have a lot in common. They’re the most abundant cannabinoids found in cannabis plants and they both have the potential to help with anxiety. They even have the same chemical structure (the atoms are just arranged differently). The main difference between THC and CBD can be summed up in one word: intoxication.
CBD can be infused into a variety of products, including vape juice, edibles, capsules, and CBD oil tinctures. Photo by: Gina Coleman/Weedmaps
How does smoking CBD feel?
Hemp flower and high-CBD flower may look the same, but they’re legally very different. Photo by: Gina Coleman/Weedmaps
CBD is often touted as nonpsychoactive or having no psychoactive effects, but it’s more accurately described as nonintoxicating. Why? Even though CBD won’t get you high, that subtly calm feeling you might experience after taking some CBD tincture is technically a psychoactive effect. Any substance that has a direct effect on the function of the brain is considered psychoactive. By contrast, THC can be intoxicating even at low doses.
In addition to a feeling of relaxation, smoking CBD has been reported to provide quick relief of swelling and pain. Photo by: Gina Coleman/Weedmaps
According to Dr. Adie Rae, a neuroscientist and scientific adviser to Weedmaps, “The bioavailability of CBD is greater through the lungs than through the gut. Specifically, about half of the CBD you inhale makes it into the blood, but only 5% of the CBD you eat gets into your blood.” A Chemistry & Biodiversity study published in 2017 confirms this, stating that while the bioavailability can vary based on how the CBD is smoked, “smoking… provides a rapid and efficient method of drug delivery from the lungs to the brain.”