Sour Tsunami : One of the first strains bred for its CBD content, this cultivar typically sports a 1:1 ratio of CBD to THC.
(Photo by: Gina Coleman/Weedmaps) Photo by: Gina Coleman/Weedmaps
Flower : Combusting or vaporizing CBD weed allows users to feel the potential therapeutic effects of CBD almost immediately.
Industrial hemp and whole-plant marijuana
CBD can affect liver function, however. Similar to grapefruit, CBD can inhibit certain drug-metabolizing enzymes in the liver , resulting in much higher levels of some prescription medications in the bloodstream. If you are taking medication, check with your physician before using CBD.
CBD fits the definition of a psychoactive substance as it can subtly alter perception and mood. However, it’s important to reiterate that unlike weed, CBD does not cause intoxication. CBD is a non-intoxicating substance, so it cannot stimulate the level of sensory and psychological effects that THC does.
CBD has some other very important roles outside the ECS. For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A) in mice, which may explain its supposed effects on depression and anxiety . It also acts at the peroxisome proliferator-activated receptors (PPARs) in mice, which may indicate its usefulness in fighting inflammation.
The relationship between THC and CBD is complex, but in short, CBD appears to minimize some of THC’s less desirable effects, such as paranoia , heart palpitations, and impaired thinking. A combination of THC and CBD may offer enhanced therapeutic value to patients . This phenomenon of cannabis-derived molecules working more synergistically together than they do in isolation is commonly referred to as the entourage effect .
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a "high." According to a report from the World Health Organization, "In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD."
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The bottom line on cannabidiol
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit.
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.
Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.