Many people turn to CBD with and without medical advice. Those who may not use CBD may use cannabis to control their pain, weight loss, nausea, and other side-effects of their illness. Cannabis or CBD might play a role in increasing the quality of life for patients with IBD.
All of their products are minimally processed and grown on family-run farms.
Medterra manufactures broad-spectrum oil with entourage effects, plus its wide variety of products are all CO2 extracted to yield the best CBD oils for the money.
Research on CBD and Crohn’s Disease
Another study demonstrated  a role for cannabinoids in reducing intestinal permeability and reducing inflammation and regulation of intestinal bacteria, especially as it related to alcohol use disorders. All of these factors can play a role in symptomatic flare-ups in patients with IBD.
Established in 2018, Spruce is a CBD brand based in Raleigh, North Carolina. The company prides itself on making American-made CBD products and some of the best CBD oils available.
In the lower digestive tract, endocannabinoids are supposed to protect the gut and reduce motility and inflammation – both of which may lead to the disabling pain associated with ulcerative colitis and Crohn’s disease. Analgesic properties  of cannabis products are proposed to be via the TRPV1 endocannabinoid system receptors, and relief is often sought using cannabis oils for the abdominal pain that accompanies the cramping of IBD. The anti-inflammatory effect cannabidiol (CBD) has on tissues should help decrease intestinal inflammation-associated pain. CBD has potent anti-inflammatory activities on pro-inflammatory mediators, making it an ideal choice for the treatment of people with IBD. Read on to find out the best CBD oil dosage for Crohn’s disease.
The company does third-party testing with the Certificate of Analysis on its products’ purity for downloading off their website. Their Certificate of Analysis outlines the presence of cannabinoids, terpenes, solvents, pesticides, microbial growth, and heavy metals.
Introduction: Cannabis use among inflammatory bowel disease (IBD) patients is common. There are many studies of various laboratory models demonstrating the anti-inflammatory effect of cannabis, but their translation to human disease is still lacking.Areas covered: The cannabis plant contains many cannabinoids, that activate the endocannabinoid system. The two most abundant phytocannabinoids are the psychoactive Tetrahydrocannabinol (THC), and the (mostly) anti-inflammatory cannabidiol (CBD). Approximately 15% of IBD patients use cannabis to ameliorate disease symptoms. Unfortunately, so far there are only three small placebo controlled study regarding the use of cannabis in active Crohns disease, combining altogether 93 subjects. Two of the studies showed significant clinical improvement but no improvement in markers of inflammation.Expert opinion: Cannabis seems to have a therapeutic potential in IBD. This potential must not be neglected; however, cannabis research is still at a very early stage. The complexity of the plant and the diversity of different cannabis chemovars create an inherent difficulty in cannabis research. We need more studies investigating the effect of the various cannabis compounds. These effects can then be investigated in randomized placebo controlled clinical trials to fully explore the potential of cannabis treatment in IBD.
Keywords: Cannabis; Crohn’s disease; inflammatory bowel disease; marihuana; ulcerative colitis.