Conclusion: Topical CBD may be beneficial at relieving arthritis but no high-quality human studies prove this.
CBD (short for cannabidiol) is one of over 200 chemical compounds known as cannabinoids that are found in cannabis. It is the second most prevalent active compound found in cannabis, behind THC (tetrahydrocannabinol), which is the compound in cannabis that has psychoactive properties and gives people a high. 2
Conclusion: CBD may be beneficial at relieving pain but no high-quality human studies prove this.
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
CBD has also been investigated for use in other forms of treatment-resistant epilepsy, usually in addition to conventional epilepsy medications. Results varied, but several trials showed CBD significantly reduced seizure frequency by almost 44% in most people. 3
Beneficial effects on anxiety after taking CBD were reported in an observational study where 21 patients out of 400 had anxiety. 8
In June 2018, the FDA approved Epidiolex (a plant-based formulation of CBD) to treat seizures for people 2 years of age and older with Dravet syndrome and Lennox-Gastaut syndrome (LGS), which are two rare forms of epilepsy.
Studies on immune responses and inflammation demonstrate that CBD is anti-inflammatory and immune suppressive  . The anti-inflammatory properties of CBD help suppress the immune system by reducing inflammation, which effectively strengthens the immune system.
A 2012 study  where animals were induced with carcinogens in a lab and then treated with CBD showed that they were less likely to develop colon cancer. Several studies have shown that THC can help reduce or prevent tumors. In a 1996 study  , animal models were used to prove that CBD helped reduce the incidence of both hepatic adenoma and benign tumors.
CBD may work as an antioxidant and help reduce oxidative stress, a condition that occurs when the body has too many free radicals making it difficult for antioxidants to neutralize them. Hence, owing to the rising of toxicity in our environment, it’s a comparatively recent problem.
21. Immunomodulatory Effects
Like with helping people with relief from inflammation, multiple sclerosis, chronic pain, and cognitive impairment, a recent study that focused on using CBD to treat Alzheimer’s  found that CBD has effects that can effectively treat disorders in the nervous system including Alzheimer’s.
Here Are Top 22 Health Benefits Of CBD Oil:
In an animal trial done in 2005, low-dose oral cannabinoids helped slow down the progression of atherosclerosis  . Eventually, it was suggested that there was a substantial therapeutic potential for conditions atherosclerosis. Another animal study in 2007 showed that CBD had cardio-protective effects  in case of heart attacks.
IBS attacks are highly correlated with anxiety, and the episodes can either be triggered by dietary indiscretions like overeating or specific foods. If gastrointestinal insults like antibiotics or food poisoning are significant, the attacks may persist but only indefinitely.
Many of these interactions are mild and require no adjustment to treatment. Others may require a drug substitution or the separation of doses by several hours.
As CBD grows in popularity, so does the research on it but there are currently few clinical studies on the effects of CBD oil. As such, some of these claims are better supported by studies than others.
CBD oil comes as full-spectrum oils or in forms that contain CBD isolates. Unlike isolates, which contain CBD only, full-spectrum oils contain a variety of compounds found naturally in the cannabis plant, including proteins, flavonoids, terpenes, and chlorophyll. Alternative practitioners believe these compounds offer more substantial health benefits, although there is no clear evidence of this.
Dosage and Preparation
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
Cathy Wong is a nutritionist and wellness expert. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health.
There have also been suggestions that CBD may aid in the treatment of cannabis and nicotine addiction. Further research is needed.
According to the investigators, men provided 300 mg of CBD exhibited less anxiety than those given a placebo. Interestingly, those provided 100 mg or 600 mg of CBD oil did not.