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There is some evidence that CBD interacts with seizure medications such as Onfi (clobazam) and boosts their concentration in the blood. Further research is needed.

Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.

CBD oil may also increase liver enzymes (a marker of liver inflammation). People with liver disease should use CBD oil with caution, ideally under the care of a doctor who can regularly check blood liver enzyme levels.

Possible Side Effects

The findings suggest that CBD oil may be a suitable complementary therapy for people whose hypertension is complicated by stress and anxiety. However, there is no evidence that CBD oil can treat hypertension on its own or prevent hypertension in people at risk. While stress is known to complicate high blood pressure, it cannot cause hypertension.

CBD oil can interact with certain medications, including some drugs used to treat epilepsy. CBD inhibits an enzyme called cytochrome P450 (CYP450), which metabolizes certain drugs. By interfering with CYP450, CBD may either increase the toxicity or decrease the effectiveness of these drugs.

Here is just some of what the current evidence says.

Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.

Digestive Issues

Some people experience skin irritation when using topical oils containing CBD, possibly due to an allergy. Start with using a small amount to see how your skin reacts to it, and keep an eye on any changes.

Brain, Behavior, and Immunity: “Omega-3 Supplementation Lowers Inflammation and Anxiety in Medical Students: A Randomized Controlled Trial.”

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In general, hemp seed oil is safe to ingest or use topically, but there are a few things to note if you decide to start taking hemp oil. Pay attention to the following potential risks of hemp oil:

Current Pharmaceutical Biotechnology: “Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.”

Many of these nutrients provide the body necessary minerals and also contribute to overall health. Note that hemp seeds contain a significant amount of iron (20 % of your recommended daily diet). This helps prevent iron deficiency, or anemia.

Hemp oil, also known as hemp seed oil, is made from hemp, a cannabis plant like the drug marijuana but containing little to no tetrahydrocannabinol (THC), the chemical that gets people “high.” Instead of THC, hemp contains cannabidiol (CBD), a chemical that has been used to treat everything from epilepsy to anxiety.

CBD is a compound called a cannabinoid, says Jordan Tishler, MD, a Harvard-trained doc who is an expert on using cannabis as medical treatment. It can be extracted from hemp or marijuana, two different plants from the Cannabis sativa L. (“cannabis”) species. The big difference between the two: Marijuana contains higher levels of tetrahydrocannabinol (“THC”), the compound responsible for the psychoactive properties of pot (a.k.a., the stuff that makes you high). Hemp, on the other hand, is naturally very low in THC (0.3 percent), says Tishler.

“It probably should be called snake oil,” says Tishler. (So. save your cash.) Not only does hemp oil not have any real health benefits, but it may contain stuff that’s actually bad for you. “At the moment what you can buy is less regulated than the potato at the supermarket,” says Tishler. When hemp oil is extracted, there’s a risk that pesticides, plastics, and heavy metals could make their way in, says Tishler.

What is hemp oil—and is it different from CBD oil?

Omega-3 and omega-6s have been shown to help treat conditions like atopic dermatitis (a.k.a. eczema), which can leave your skin dry and itchy. GLA in particular has been shown to improve dry skin and eczema. One 2005 study even found people who consumed hempseed oil for 20 weeks had a reduction in oil and reduced the symptoms and appearance of eczema after 20 weeks. But that research is preliminary, Tishler points out.

It seems like everyone and her sister (and grandma, and aunt and second cousin twice-removed, and . you get it) is sprinkling CBD oil in her smoothies because of claims it can help with everything from pain to anxiety. But what about CBD’s sister: hemp oil? Are hemp oil benefits legit? Proponents say it can help with sleep and anxiety, balance your hormones, make your skin glow, and protect your ticker. But here’s what you should know before you start drizzling it on top of your food or slathering it on your skin.

Fatty acids and GLA may also help curb the physical and emotional pain linked to PMS. Here’s why: One of the causes of PMS is a hormonal imbalance that leads to a lack of GLA in the body. Research on GLA has shown to help alleviate the symptoms of PMS by bringing hormone levels back into balance. But so far, studies haven’t found ingesting or slathering on hemp oil itself will have this effect.