Schwab US, Callaway JC, Erkkilä AT, Gynther J, Uusitupa MI, Järvinen T. Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors. Eur J Nutr. 2006;45(8):470-7. View abstract.
Rodriguez-Martin NM, Toscano R, Villanueva A, et al. Neuroprotective protein hydrolysates from hemp (Cannabis sativa L.) seeds. Food Funct. 2019;10(10):6732-6739. View abstract.
Moccia S, Siano F, Russo GL, et al. Antiproliferative and antioxidant effect of polar hemp extracts (Cannabis sativa L., Fedora cv.) in human colorectal cell lines. Int J Food Sci Nutr. 2019:1-14. View abstract.
Hemp is used for constipation, high cholesterol, eczema (atopic dermatitis), arthritis, and other conditions, but there is no good scientific evidence to support these uses.
Jin S, Lee MY. The ameliorative effect of hemp seed hexane extracts on the Propionibacterium acnes-induced inflammation and lipogenesis in sebocytes. PLoS One. 2018;13(8):e0202933. View abstract.
Allergy to cannabis: People who are allergic to cannabis might also be allergic to hemp. Use hemp with caution if you are allergic to cannabis.
House JD, Neufeld J, Leson G. Evaluating the quality of protein from hemp seed (Cannabis sativa L.) products through the use of the protein digestibility-corrected amino acid score method. J Agric Food Chem. 2010;58(22):11801-7. View abstract.
Unfortunately, the answer isn’t a simple “yes” or “no.”
More research will need to be done to definitively say whether CBD oil increases or decreases appetite in its users. Ultimately, CBD oil’s effect on appetite could just vary from person to person based on their biology or, could very well not be due to the CBD at all. Like diarrhea, an increase or decrease in appetite following CBD consumption could be the result of another ingredient in the CBD product you’re consuming.
Possible CBD Oil Side Effects
Diarrhea is a potential side effect that has been linked to the use of CBD oil. The 2015 study in which diarrhea was reported as a side effect was conducted on people between the ages of 1 and 30 who had severe epilepsy. The study examined the effects of the epilepsy drug Epidiolex , which contains cannabidiol (CBD) as an active ingredient. Of the 214 participants, 19% reportedly experienced diarrhea. It is not entirely clear as to whether CBD was responsible for this side effect, as it has not occurred in other studies.
CBD oil products that contain no THC or only trace amounts pose a minimal risk to the consumer. But there are some people who should be careful.
On a closing note, the National Cancer Institute has even stated, “Because cannabinoid receptors, unlike opioid receptors, are not located in the brainstem areas controlling respiration, lethal overdoses from Cannabis and cannabinoids do not occur.”