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high cbd oil effects

Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.

However, the effect of CBD on each addiction type was often very different. With opioid addiction, for example, CBD showed little effect in minimizing withdrawal symptoms in the absence of THC. By contrast, CBD on its own appeared effective in minimizing drug-seeking behaviors in users of cocaine, methamphetamine, and other psychostimulant drugs.

Human studies evaluating the use of CBD in treating chronic pain are lacking. Those that do exist almost invariably include THC, making it difficult to isolate CBD’s distinct effects.

Possible Side Effects

Remember, because CBD oils are largely unregulated, there is no guarantee that a product is either safe or effective.

CBD oil comes as full-spectrum oils or in forms that contain CBD isolates. Unlike isolates, which contain CBD only, full-spectrum oils contain a variety of compounds found naturally in the cannabis plant, including proteins, flavonoids, terpenes, and chlorophyll. Alternative practitioners believe these compounds offer more substantial health benefits, although there is no clear evidence of this.

CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.  

Scientists believe that CBD reduces nerve pain by binding to glycine receptors in the brain that regulate the speed at which nerve signals pass between nerve cells.

With the passing of the Farm Bill in December 2018, industrial hemp became a legal agricultural commodity in all 50 states. While the DEA still considers CBD to be a Schedule I controlled substance, it clarified in a memo that trace amounts of CBD found in hemp stalks or seeds were legal.

Although THC is best known for its mind-altering euphoria, it too has important medical benefits. There’s some overlap in what CBD and THC can treat, but THC is particularly effective in relieving nausea, appetite loss, insomnia, among other symptoms. Many patients find that a balance of CBD and THC offers the best symptom relief as the two work together synergistically.

What’s the difference between CBD and THC?

However, the legality of hemp-derived CBD may vary from state to state, so it’s important to check your state’s laws before stocking up on hemp-derived CBD products.

In less than two years, Charlotte went from a monthly seizure count of 1,200 to about three. Other success stories followed and more parents have begun to speak out, particularly parents desperate for access to this life-saving treatment.

(The Cannabiz Agency/iStock)

Humans and other mammals have an internal network of chemicals and receptors in the central and peripheral nervous systems called the endocannabinoid system. These receptors, named CB1 and CB2, bind with molecules called ligands (in this case endogenous cannabinoids like anandamide) to control the release of neurotransmitters like glutamate and dopamine. The endocannabinoid receptors, ligands, and certain enzymes work in concert to affect a variety of processes in the body, including thought, memory, mood, pain management, and appetite.

Vaping and smoking expedite the active ingredients to the brain (through the lungs) much more quickly than other delivery methods. Using CBD oil tinctures sublingually (under the tongue) is the second-fastest method (though still much slower than inhalation). Using CBD edibles or swallowing a tincture is the slowest, since the CBD must process through the liver before reaching the bloodstream and brain.

Does CBD get you high?

Cannabinoids created outside the body—called exogenous cannabinoids—like CBD and THC from the cannabis plant, can also bind with the CB1 or CB2 (and other) receptors to produce various effects and moderate some physical functions. THC can relieve nausea and increase appetite, and both CBD and THC are effective for pain relief. CBD is an antioxidant and an anti-inflammatory, and has proven medically effective in treating certain seizure disorders.

Because CBD is an anti-inflammatory, it can reduce pain and relax the body. That, along with the stress and anxiety relief, may be noticeable. A first-time user of CBD tincture and CBD capsules told Vaping360 that he felt “super relaxed, no anxiety, no pain, and almost like I was floating.”

In addition to CBD-rich flowers, CBD can be consumed in vape juice (e-liquid), CBD oil tinctures, edible products like gummies and drinks, in capsules, and in a wide variety of topical lotions and creams. CBD e-juice can be vaped in a regular vape mod or pen, or taken orally like a tincture. But even if its label calls CBD e-liquid “oil,” it isn’t really oil; e-liquid is made with propylene glycol and vegetable glycerin. Tinctures are made with actual CBD oil and carrier oils like MCT or coconut oil, and can only be consumed orally, never vaped. Inhaling real oils can be dangerous.