When cannabidiol is introduced to the endocannabinoid system, it inhibits the absorption of anandamide, a natural cannabinoid molecule that regulates pain. Photo by: Gina Coleman/Weedmaps
We’ve covered the factors that determine how long it takes for CBD to work, but what about how long it takes to get CBD out of your system? Again, it depends on many of the aforementioned factors that determine the effectiveness of the cannabinoid itself.
The method of consumption matters
Studies show that when CBD compounds are metabolized by the liver, it undergoes what is called the “first pass effect,” where enzymes in the liver reduce CBD concentration before the remainder is finally sent to the bloodstream and circulated throughout the body.
In recent years, cannabidiol (CBD) oil has skyrocketed in popularity. Knowledge about how it works in the human body, however, has accelerated at a snail’s pace. If you’ve ever wondered, “How long does it take for CBD oil to work?” or “How long will the effects of CBD oil last?” you’re not alone.
Body fat influences the amount of CBD you need to feel an effect. The larger the body mass, the more CBD required to feel potential effects. Bodyweight and mass also affect how long CBD will remain in your system. Like THC, CBD is stored in fat cells and gradually eliminated from the body through urine and feces.
This increased interest in CBD oil has raised many questions, with one of the most common being, “how long does CBD last?” If you’ve never taken CBD before, knowing how long its effects will linger is important for determining your ideal dosage, and ultimately helping you decide if CBD oil is right for you.
The more CBD oil you take, the longer it will take for your body to process it, and the longer the effects will last.
CBD Delivery Methods and Duration of Effects
For example, CBD’s effects from edible preparations of CBD oil, like gummies , can last between 4-6 hours while a CBD oil transdermal patch can last up to 48 hours. On the other hand, a CBD vape oil’s effects can disappear within an hour while a CBD oil tincture can last 2-4 hours.
With cannabidiol (CBD) oil becoming more widely available, it is being sought out by an ever-growing number of people due to its potential health benefits. The list of CBD’s reported therapeutic uses is also ever-growing, leading many people to consider trying it for the first time.
Another factor that plays a role in how long CBD lasts in the body is lifestyle and activity level. If you lead an active lifestyle, your body is likely to process CBD more quickly because your metabolism will be faster, resulting in a reduced duration of effect.