CBD products are not subject to regulation because they are marketed as supplements, which means that you don’t know if you are really getting what is described on the label. Because these products are not regulated, you have no way of knowing for sure what you are getting in terms of purity, safety, and dosage.
CBD, on the other hand, is purported to have a wide range of health benefits without these psychoactive effects. Some research suggests that CBD has antidepressant-like effects, which means it may hold promise in alleviating symptoms of depression.
CBD holds promise, but that does not mean that you should turn to cannabidiol products over traditional treatments for depression.
The bottom line when it comes to CBD’s potential as a treatment for depression is that more research is needed. Most of the evidence supporting CBD’s antidepressant effects comes from animal studies or small trials, and one of the largest reviews of the research found that the available evidence is not strong enough to recommend CBD as a treatment for depression.
Another study found that CBD had a “clear anti-stress effect,” which might play a role in reducing stress levels that contribute to feelings of anxiety and depression.
So how does CBD compare to traditional antidepressants? True comparisons of the effects are not yet possible simply because there is not enough research on CBD’s effects.
Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
We recommend the high potency range from Royal CBD as the best anti-anxiety and anti-depressant CBD oil overall. The most popular option is the low-cost 1000 mg bottle of oil.
GABA is important because it’s the primary inhibitory compound in the brain. It works in direct opposition to glutamate and norepinephrine, causing electrical activity to slow down. It’s responsible for reversing the stress response.
Gold Bee oils also contain other terpenes, such as limonene of pinene that offer anti-depressant effects.
CBD & depression: How it works
Stress isn’t inherently negative. It’s designed to help us get out of or avoid dangerous situations — like coming face to face with a hungry tiger.
When shopping for CBD oils, it’s best to look for a product that employs a full-spectrum hemp extract, is made from organic hemp, and provides clear evidence of independent testing.
Other key neurotransmitters, including dopamine and serotonin, fall out of balance from causes like chronic stress, insufficient sleep, or as a side-effect from certain prescription anxiety medications.
Blessed CBD oils are available in three different potencies:
CBD as a tool in the fight against depression is now a key area of interest for consumers and researchers alike. Photo by: Gina Coleman/Weedmaps
Studies have shown that CBD offers a promising therapeutic profile as a potential fast-acting antidepressant treatment option. Photo by: Gina Coleman/Weedmaps
Overall, anecdotal reports offer insight, as many patients have reported relief following treatment with CBD-rich cannabis products. These products are increasingly being used to treat symptoms of depression, and research indicates cannabinoids may support a more comprehensive, long-term recovery treatment plan.
Yoon also acknowledged the limits of medical research.
Numerous animal models have shown that CBD may yield great psychiatric potential, offering anti-anxiety and antidepressant-like properties. The effect of CBD on serotonin 1A receptors may influence be key.