Animal studies have shown that CBD has anti-inflammatory effects and works on the endocannabinoid and pain-sensing systems to relieve pain.
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
Conclusion: CBD is unlikely to be effective by itself for nausea and vomiting. The combination of THC and CBD does seem to be effective for nausea and vomiting.
Animal studies showed that topical CBD applications relieve pain and inflammation associated with arthritis with few side effects. The topical application of CBD is beneficial because CBD is poorly absorbed when taken by mouth and can cause gastrointestinal side effects. 6
CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.
In addition, the stroke volume (the amount of blood remaining in the heart after a heartbeat) was significantly reduced, meaning that the heart was pumping more efficiently.
Here is just some of what the current evidence says.
CBD oil can interact with certain medications, including some drugs used to treat epilepsy. CBD inhibits an enzyme called cytochrome P450 (CYP450), which metabolizes certain drugs. By interfering with CYP450, CBD may either increase the toxicity or decrease the effectiveness of these drugs.
Potential drug-drug interactions with CBD include: