Clifton says that she remains undecided about nanotechnology, but she says that some of her patients are enthusiastic about the formulations. “A number of my patients swear by the use of nanotechnology to make their CBD more effective,” she said. However, she notes that the human data on CBD nanotechnology is pretty much nonexistent, though cellular data shows promise.
Kurek begins by noting that nano-sized delivery technologies are not unique to CBD and are widely used by pharmaceutical companies to ensure bioavailability. “Nano CBD is a CBD molecule coated with very small particles, such as liposomes or lipid nanoparticles (LNPs), that stabilize the CBD and can move in our blood faster than ‘naked’ CBD, to effectively reach the target,” he explained.
The technology used in Nano CBD isn’t new.
A challenge with cannabinoids generally — regardless of how they’re processed — is cannabinoid degradation. Once cannabis is harvested it begins the degradation process, meaning that the potency of the product, whether it is water or an edible, will decline. Many factors contribute to this process, but the top four are UV light, airflow, humidity, and temperature.
The bottom line is that there just isn’t much research for a persuasive argument either way. The only thing consumers can really do is to shop thoughtfully for CBD — nano or not — and buy from U.S. companies that can easily show you their third-party lab results and certificate of analysis.
Kurek adds, “Nano CBD is a CBD molecule packaged in nano-carriers that are the size of about 100 nanometers — or one-billionth of a meter — which allows the “package” to stay in the body for a longer time and to slowly release the intact CBD in the targeted tissue.” To illustrate his point, he mentions a 2017 study that reported a 600% increase in bioavailability of oral Nano CBD compared to CBD in a rat model.
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Nano-enhanced CBD oil offers much higher bioavailability and rapid absorption than CBD oil. In simpler terms, nano-enhanced CBD oil is “more absorbing” than conventional CBD oils.
Quick Recap on CBD
Nanoparticle technology is the most advanced/latest CBD development process. The technique involves covering liposomes with microscopic fat which results in a more immediate and stronger effect.
With most isolated CBD tinctures, only a small amount of oil consumed ever affects your body. These enhanced product uses a Nano-liposomal delivery system, allowing you to absorb and reap the benefits fully. You absorb nano-enhanced CBD into your body at a rate close to 100%!
Despite seeming like a new craze, CBD has its roots in a part of human’s body that many leave dormant. CBD interacts with the body through the endocannabinoid system. Found in humans, and all mammals, this system is made up of millions of cannabinoid receptors located through the central nervous system (CB1) and immune system (CB2) that act as communication for your neural networks.