In larger studies on CBD treatment for epileptic patients, it was associated with drowsiness, decreased appetite and diarrhea in up to 36 per cent of people, the Mayo Clinic authors said, adding the side-effects were less severe and frequent compared with a conventional anticonvulsant medication.
As well, no other "cannabis-related drug (including fresh or dried marijuana or cannabis oil) has been approved to be marketed as a drug for therapeutic use and sale in Canada," Health Canada said.
People should talk to their physician, nurse or pharmacist to discuss potential drug interactions when determining whether to try CBD.
How do you know what's in the product?
"If you're taking those medications to begin with and you use cannabis, we'd expect that those side effects would get worse," said Kelly Grindrod of the University of Waterloo's School of Pharmacy.
Cannabidiol, or CBD oil, is promoted for a wide range of medical conditions. Recently, a review for doctors weighed the science behind the claims.
"A lot of CBD oil can have very little or contain lots of THC, so you must be very careful," Gobbi said. "We need more quality control."
There are anecdotal reports from users of CBD helping with certain types of pain, such as nerve-related back pain.
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