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cbd oil for seizures in children

“The resultant inability to provide evidence-based dosing and therapeutic monitoring of cannabis-based products in children … leads to a reluctance by many physicians to authorize CBD-enriched cannabis herbal extract to these patients,” the researchers wrote.

The trial is still recruiting at clinical sites in British Columbia, Manitoba, Quebec and Saskatchewan. More information is available here.

Caregivers were asked to monitor and record daily seizure frequencies throughout the study.

At the maximum tested dose (10–12 mg/kg per day), CHE led to an average seizure reduction across all children of 74%, with three being seizure free.

In general, CHE with CBD equivalent dose of 10–12 mg/kg per day was found to lower electrical activity in the brain, as determined by electroencephalography (EEG).

Dravet syndrome typically begins in infancy and can lead to intellectual disability and frequent, prolonged seizures, noted a team of researchers led by Dr. Ian Miller, from Nicklaus Children’s Hospital in Miami.

“The children in this study had already tried an average of four epilepsy drugs with no success and at the time were taking an average of three additional drugs, so to have this measure of success with cannabidiol is a major victory,” Miller said in a meeting news release.

Total seizures fell 47% in the high-dose group, 56% in the low-dose group, and 30% in the placebo group.

The most common side effects were decreased appetite, diarrhea, sleepiness, fever and fatigue. Serious side effects occurred in 25% of the high-dose group, 20% of the low-dose group, and 15% of the placebo group.

One specialist in epilepsy care said the new study offers findings “very similar to the previously reported data” that led to Epidiolex’ approval.

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driving with cbd oil

CBD isn’t directly psychoactive like its cannabinoid cousin THC. However, it can impact mood and possibly alertness by catalysing alterations in brain chemistry.

So, we’ve pretty much given CBD the clear when it comes to driving safety, but then the law comes in and complicates things. Many CBD oils contain small amounts of THC, with many European countries allowing legal trace amounts of between 0.2–0.6% of the cannabinoid. These amounts are so small that they are not likely to produce any intoxicating effect, unless the oil is consumed in vast quantities. Even in this event, the sedation of a high CBD dose will probably be the primary effect here.


Furthermore, CBD is also reported to act as an allosteric modulator, meaning it can either enhance or inhibit receptor transmission. More specifically, CBD works [2] as a positive allosteric modulator of the GABA-A receptor. In doing so, CBD causes this receptor to bind more easily with the neurotransmitter GABA. GABA has inhibitory effects on nervous system activity, inducing states of calm and relaxation.

CBD is a popular cannabinoid from the cannabis plant known for its medicinal value. Although CBD oil is not intoxicating, users should be aware of possible side effects—as well as the presence of THC—to avoid getting in trouble on the road.

CBD is known to affect brain serotonin receptors when ingested in high doses, an action partly responsible for the molecule’s anti-anxiety effects. Additionally, CBD can work as a reuptake inhibitor [1] in the brain, allowing it to raise and maintain high levels of anandamide, an endocannabinoid that is molecularly similar to THC. CBD also inhibits the reuptake of adenosine, increasing levels of the molecule in the brain and contributing to further anti-anxiety effects.

Although CBD is a natural compound, it is extracted from the hemp plant. The hemp plant is known for being the source of cannabis and THC (tetrahydrocannabinol). With this in mind, it is understandable why so many people question the legality of CBD oil and whether it is safe to drive after taking it.

Can you drive safely after taking CBD oil?

CBD oil is non-intoxicating and will not affect your ability to drive. The majority of CBD oils do contain traces of cannabinoids which includes CBN and THC. However, the content should not be any more than 1mg in any one container.

CBD oil has become increasingly popular. Although it is easy to purchase and is readily available on shop shelves and across the internet, there are still questions being asked.

Is CBD oil safe when driving?

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cbd oil for wounds

The cannabis oil treatment also reduced the man’s pain after the cancer created a hole in his right cheek, according to the report published in the January issue of the Journal of Pain and Symptom Management. Studies have suggested that marijuana may work to treat cancer patients’ pain.

However, about a month after the man started using the oil, he was admitted to a hospital because his overall condition had deteriorated. He died from cancer three weeks later, according to the report.

“Ancient cultures used cannabis extracts on wounds,” Maida said.

A middle-age man in Canada with oral cancer found that medical cannabis oil may have helped to slightly reduce the size of a wound that his cancer caused on his cheek, according to a new report of his case.

The doctor prescribed vaporized medical marijuana for the man, which the man then used for the next few months. The marijuana seemed to help alleviate the pain significantly, and allowed the man to reduce the doses of opioids he was taking. However, the wound in his cheek grew and the cancer eventually eroded through his cheek, creating a hole, which prevented the man from continuing to use vaporized marijuana.

Research shows that CBD cannabis has strong analgesic, anti-inflammatory and antiseptic properties. The body’s endocannabinoid system, involved with the process of healing itself, is enhanced with the application of CBD topicals. Often healing can often occur more quickly with CBD than over-the-counter medicines.

Treating wounds and skin conditions with CBD topicals has been done through the millennia. They come in the form of lotions, balms, creams, oils or salves that are applied directly to the injury. The definition of injury in conjunction with these products can be cuts; lacerations; burns; puncture wounds; surgery and malignant wounds; injured muscles; or conditions such as arthritis, neuropathy, psoriasis. CBD is a versatile and effective wound treatment.

CBD’s sterilizing properties protect the area while promoting skin cell growth, and even desensitizing your body to pain. It also sanitizes the wound providing antibacterial protection as the wound heals. CBD is especially helpful in treating burns. In addition to helping them heal faster, continued use keeps the burn clean, reduces pain and inflammation and may prevent scarring.

In the case of a malignant wound, or an open cancerous skin lesion, which may be draining, a case report published in January 2017 in the Journal of Pain and Symptom Management suggests topical cannabis may aid in the treatment of such wounds. The report told of a 44-year-old man with a cancerous lesion on his cheek that had been treated with chemotherapy, surgery and radiation. All to no avail. He turned to CBD for pain relief and found that in addition to relieving his pain, the lesion began to heal.

Athletes or those suffering from arthritis have found relief with CBD. Individuals, who because of illness or medical treatment find their skin feeling and looking dry and lifeless, have used CBD lotion to protect skin. In doing so, they find it also replenishes the skin.

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cbd oil como se toma

Cada tintura de aceite JustCBD ES es:

Puede que te preguntes cuál es la diferencia entre los aceites de tintura de CBD y el aceite de CBD estándar. Aunque los dos productos tienen muchas similitudes, la distinción clave con el aceite de tintura de CBD es que se le han añadido aceites y sabores naturales para mejorar la potencia y el sabor del producto.
Y en JustCBD, tenemos una amplia selección que se adapta exactamente a lo que buscas, incluyendo nuestra miel dulce y el auténtico aceite de coco. El aceite de tintura de CBD también contiene una base de alcohol, a diferencia del aceite de CBD que tiene una base puramente oleosa. La base de alcohol permite una máxima absorción del CBD en todo el cuerpo, además de prolongar su vida útil. En otras palabras, el aceite de tintura puede durar más tiempo, y te dará una verdadera ventaja por tu dinero.

Uno de los numerosos beneficios de la tintura de CBD en el Reino Unido es que una persona nunca tiene que preocuparse por tomar demasiado. Ni siquiera es posible tener una sobredosis de CBD natural. Sin embargo, siempre es mejor empezar lentamente con una pequeña cantidad de CBD. Con el tiempo, una persona puede experimentar con potencias más altas hasta encontrar sus selecciones ideales. Sólo hay que tener en cuenta que no hay dos cuerpos iguales. Lo que puede funcionar de maravilla en una persona puede no producir ningún resultado en otra. De hecho, es posible que el CBD sólo funcione en el 80% de las personas. Al menos, la mayoría de los afortunados pueden comprar CBD online para tranquilizar sus mentes y cuerpos. ¿Se pregunta cuántas gotas de CBD debería tomar? Se sabe que usarlo una, si no dos veces al día, ayuda a la gente a sentarse, relajarse y disfrutar de un estado de ánimo tranquilo.

¿Cómo se hace el aceite de CBD?

Las tinturas de aceite de CBD puro del mercado se crean a partir del cáñamo, en lugar de la marihuana rica en THC, utilizando un método de extracción de CO2 de las plantas de cáñamo CBD. Las auténticas tinturas de CBD poseen aproximadamente un 75% de aceite MCT. Los comentarios de los consumidores reales afirman que son lo suficientemente cómodas como para llevarlas en el bolsillo o en el bolso, y que tienen una larga vida útil.

Disfrutar del aceite de CBD puro es rápido y fácil. Todo lo que necesitas es un cuentagotas líquido de 1mg para rellenar con aceite de CBD de alta calidad. A continuación, deja caer un poco bajo la lengua. Intenta mantenerlo en la boca durante 30 o 60 segundos antes de tragarlo. Esto permitirá que el CBD se absorba en tu sistema. Además de usar un cuentagotas, algunas personas también disfrutan echándolo en su café, té y batidos de frutas. El consumidor puede elegir entre el aceite de coco, el aceite de semillas de cáñamo y la miel líquida en frascos de 30 ml. Las potencias van desde 50 mg hasta la friolera de 1500 mg. Independientemente del dispositivo de administración o del sabor, los efectos positivos que pueden tener algunos beneficios para la salud deberían sentirse en poco tiempo.

Todos nuestros aceites de CBD se fabrican en los Estados Unidos. Tanto si usas el CBD con fines recreativos como medicinales, sólo utilizamos los mejores ingredientes para garantizar que nuestros productos de CBD sean de la máxima calidad. Nos esforzamos por mantener nuestra excelente reputación en la venta de productos de cáñamo de primera calidad. Por eso sólo utilizamos cáñamo nacional cultivado aquí mismo, en los Estados Unidos. No sólo hemos establecido relaciones de confianza y estrechas con los agricultores con los que trabajamos, sino que JustCBD confirma que nuestro cáñamo está libre de productos químicos no deseados, como los que se encuentran en los pesticidas.

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Como alternativa a los aceites y tinturas de CBD, mucha gente prefiere vaporizar el CBD. Esto se debe a que la ingesta de aceite de CBD a través del vapor es la forma más rápida de iniciar los efectos del CBD en los receptores del cerebro.

Hay muchos sabores distintos, diferentes potencias y diversas cantidades entre las que elegir, por lo que los usuarios tienen una amplia gama de opciones que se adaptan a su situación económica.

#2) Vaporizadores de CBD

El CBD también puede presentarse en forma de gominolas, chocolates, té, café y casi cualquier otra cosa. Muchos fabricantes de CBD incluso ofrecen opciones sin gluten y veganas de diversos comestibles de CBD para mantenerse al día con las últimas tendencias en el consumo de alimentos y satisfacer la demanda de sus consumidores.

Sin embargo, si eres alérgico a determinados componentes o tienes una piel extremadamente sensible, podrías experimentar una reacción negativa a algunos de los ingredientes adicionales del producto elegido. Por lo tanto, debería revisar la lista de ingredientes antes de comprar productos tópicos de CBD.

Si tienes problemas médicos graves, especialmente pulmonares, debes tener mucho cuidado, ya que el aceite de CBD puede provocar tos o náuseas si lo inhalas en exceso.

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cbd oil negative side effects

Also known as “cotton mouth,” CBD can potentially cause your mouth and eyes to feel very dry, notes Dr. Brent A. Bauer via Mayo Clinic. Though this side effect is more likely to occur with THC, it can happen with CBD, as well.

There are several reasons why someone might want to use CBD. The substance can be found in a multitude of products ranging from pain-relieving creams to edible tinctures to skincare. Research is still underway, but over the last few decades scientists have become more aware of how CBD might prove beneficial when applied either topically or ingested.

Gastrointestinal Issues

CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.

“CBD is not an intoxicating substance, whereas THC is a psychoactive that can get you high,” explains Dr. Jas Matharu-Daley, a physician and consultant for a brand that specializes in CBD production.

CBD is technically an unregulated substance in the United States and therefore it ought to be used with caution. This is especially important for those taking additional medications and/or those with ongoing medical issues. That said, preliminary research on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance. Health professionals do not consider CBD a cure-all for serious medical issues, including cancer.

For most patients, these side effects occurred during the first few weeks while they were quickly raising their dosage. The symptoms typically subsided after their dosage stabilized, and lowering the dose was also an effective way of decreasing undesirable side effects. If you’re experiencing any of these side effects on your current CBD product, you might experiment with waiting it out a week, lowering your dose or trying a different type of product entirely.

In the absence of definitive, slam-dunk clinical evidence, what the general CBD community does have to work with is a great deal of preliminary scientific evidence from laboratory experiments, animal models and case studies. Hundreds of scientific papers are published annually on cannabidiol, and the vast majority continue to point at CBD’s safety & efficacy for a wide range of conditions. This preliminary scientific evidence — from animal studies and human case studies — is what gets the ball rolling towards clinical trials.

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Although CBD might be a new molecule to you, scientists have been studying it since the 1970’s, alongside its infamous sister molecule, THC. For the past few decades, lawyers, doctors, patients and politicians have all been pitting the medical potential of cannabis against its risk for recreational abuse. But all the while, evidence has been mounting that CBD offers similar — if not better — medical benefits without the downside of a “high” from THC.

The most comprehensive results available are based on Epidiolex, the FDA-approved CBD drug for childhood epilepsy. During clinical trials, youths between ages 2 and 18 were prescribed high daily doses of CBD for 14 weeks. The daily doses were equivalent to 1,360 mg for a 150-pound adult — more than is typically found in an entire bottle of CBD oil.

Clinical evidence for CBD oil

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cbd oil or tincture

Despite the wide availability of CBD products, the Food and Drug Administration (FDA) has yet to establish an official serving size for CBD, so dosing and consumption methods are a matter of individual preference and need. For those who want a more precise dosing method, CBD tincture and CBD oil are two good options. Read on to learn more about CBD tinctures and CBD oils, how they work, and how to use them.

The United States market is saturated with a seemingly endless number of CBD products, particularly since the passage of the 2018 Farm Bill. These CBD products include everything from the ever-popular CBD gummy to CBD topicals, CBD drops, CBD soft gels, CBD pre-rolls, tinctures, and oils, giving consumers numerous ways to take CBD. With so many options, it’s important to remember that there is no universal best way to consume CBD — it’s all about trying things out and discovering what works best for you.

CBD tincture vs CBD oil

Remember that a tincture is likely to have a double onset. The first onset will happen very quickly as the CBD is absorbed into your bloodstream through the tissue in your mouth, and the second onset will occur later, when the CBD you swallowed is finally absorbed via the digestive tract.

There’s also virtually zero cleanup involved with a tincture, even when taken with morning coffee or an afternoon tea. Photo by: (Gina Coleman/Weedmaps)

Ultimately, tinctures and CBD oil are similar in that they are both liquid forms of CBD extract, which can both be consumed in a variety of ways. The main differences have to do with how they are produced, and the type of liquid used to deliver the CBD to a consumer’s body.

But first, a little CBD 101…

“The rate and scale of the research just hasn’t kept pace with the interest at this point. A lot of the medical uses for cannabidiol are backed by animal studies only or really no studies. So that’s where it can be a problem.”

What are tinctures specifically?

An herbal tincture is made by using a mixture of alcohol and water to extract compounds from a plant—in this case, the cannabis plant.

“Sometimes, you will find extracts called tinctures that use glycerin, vinegar, or oil as the solvent, instead of alcohol,” Low Dog says. “These offer the advantage of being alcohol-free, but may not always offer the same potency as an alcohol-water extract.”

At a plant level, the two chemicals operate as opposites, with CBD acting as a buffer of sorts to the effects of THC. “It’s sort of a ying and yang. THC is responsible for the high and CBD doesn’t do that,” Hill explains.

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ubuntu cbd oil

Their oils come in enough flavors to fill a luau table. If we had to choose one from the bunch, it’d probably have to be pineapple. Nothing says “tropical” quite like its delicately balanced sweet-yet-tart taste. The mango and peach flavors are no slouches either, though. We’d recommend getting the Fruit Pack if possible for a real party.

Price Range: $24.99 to $299.99
Available Flavors: Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
CBD Per Serving: 2.08 mg, 5 mg, 10 mg, 16.6 mg, 33.3 mg, 66.6 mg
CBD Per Bottle: 125 mg, 300 mg, 600 mg, 1000 mg, 2000 mg, 4000 mg
Type of CBD: Broad-Spectrum
Lab Results: Available on website
Refund Policy: No refunds


Price Range: $59.99
Available Flavors: Mint, Natural, Lemon Lime, Strawberry, Watermelon, Mango, Pineapple, Peach
CBD Per Serving: 16.67 mg
CBD Per Bottle: 500 mg
Type of CBD: Broad-Spectrum
Lab Results: Available upon request
Refund Policy: 30-day return guarantee

Penguin slides right into second place on our list. It earns this spot by offering one of the most well-rounded CBD oils we’ve tried in a long time. Their broad-spectrum formula is not only potent and great tasting (we’re particularly fond of the mint flavor), it’s reasonably priced as well.

The goal at BATCH is simply to make products that work . All of their hemp is organically grown on local farms and they use only the finest organic ingredients. Nevertheless, they believe the secret to their success is taking pride in being “Midwest nice” and giving every customer the personal attention they deserve.

After realizing what CBD oil for pets is made of and that there is no reason to worry about any side effects whatsoever, you are probably wondering whether you should buy it for your animals or not. This question is not so easily answered, because it depends on what it is that you are trying to achieve when it comes to the health of your pets. There are quite a few things that CBD oil can help with and the question you need to ask yourself is whether it can help with the particular condition that you are trying to treat.

There is absolutely no reason for me to try and guess how much you adore your pets, am I right? After all, this is the kind of love that can never be appropriately described. It’s just that, there are no actual words that could describe the sentiment perfectly. And yet, we all know how it feels to have that special animal in your life.


We also all know how it feels to be responsible for that special animal and, primarily, its health. If you have been following any trends around the market these days, then you have almost certainly stumbled upon those wellness products, such as the ones found at, that people are increasingly introducing to their animals’ diet. That must have made you wonder. Should you do the same?

What’s even more important, Cannabidiol, i.e. the actual substance that the products are made of, doesn’t have the same effects as Tetrahydrocannabinol. In other words, this particular compound can’t get you high, meaning that there are no risks of giving it to your animal. That is probably the biggest concern you had when you first heard that this particular product was connected to cannabis. So, now you have nothing to worry about.

Well, since you are the one responsible for your pet’s wellbeing, the least you can do is get properly informed before deciding either on giving the animal certain products or on avoiding them. After all, your little companion certainly deserves the best and it is your responsibility to provide it with the best. So, I suggest you get acquainted with one of the newest wellness trends on the market and check if your pet would benefit from it.

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manitoba hemp oil cbd

CBD is one of more than 100 compounds in hemp known as phytocannabinoids. CBD and other phytocompounds in our Broad Spectrum Hemp Extract interact with your body’s endocannabinoid system to promote balance and well being, calm a busy mind, and restore the body after a workout.

CBD Softgels offer a consistent and reliable serving size in 15mg or 50mg CBD per serving options and are a great option for those looking for ease and convenience.

How do I choose the product that’s right for me?

CBD Oil Sprays also offer flexibility, with 5 mg of CBD in approximately 4 pumps. Both drops and sprays are good options for those wanting to experiment with their serving size.

There are no set guidelines for choosing one format (drops, sprays, or softgels), over another, but here are some factors you may want to consider:

CBD Oil Drops offer flexibility for precision serving sizes, with 10 mg, 30mg, or 50mg of CBD per 1 ml serving.

MINNEAPOLIS , May 31, 2019 /PRNewswire/ — Manitoba Harvest, the global leader in hemp foods and its partner ingredient supplier, Hemp Oil Canada, announces the completion of its safety assessment and self-affirmation that its Broad Spectrum Hemp Extract is Generally Recognized as Safe (GRAS). The self-affirmed GRAS applies to the intended use in products for the general population age 2 years and older excluding pregnant and lactating women. Manitoba Harvest unveils its complete line of Broad Spectrum Hemp Extract products, including: 15-milligram CBD plant protein powders, 10-milligram CBD oil drops, 5-milligram CBD oil spray and 15-milligram CBD oil softgel formats.

Founded in 1998, Manitoba Harvest is a pioneer and leader in the manufacture and distribution of branded, hemp-based foods. The Company’s products are the fastest growing products in the hemp food market and among the fastest growing in the entire natural foods industry. The Company’s all-natural product portfolio includes Hemp Hearts, protein powder, Granola and new to the market, Hemp Yeah! Bars and Broad Spectrum Hemp Extract with CBD, launching in June 2019 . Manitoba Harvest’s products are sold globally across 22 countries, including approximately 16,000 retail stores across the United States and Canada .

About Manitoba Harvest

The Manitoba Harvest Broad Spectrum Hemp Extract line launching this June will include Vanilla Protein Powder, Peppermint Oil Drops, Unflavored Oil Drops, Peppermint Spray and Softgels. All products are THC free, defined as having less than 0.01% THC, a differentiator for the brand.

This announcement follows a historic first for the hemp industry. Last December, Manitoba Harvest became the first company within the category to proactively gather and provide the scientific evidence necessary to affirm the sought-after Food and Drug Administration designation of GRAS Notified, for its hemp hearts, hemp seed oil and hemp protein powder.

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how do i use cannabis oil

As a Florida medical marijuana patient, there are more options than ever when it comes to cannabis consumption. Aside from smoking cannabis, there are now concentrates, edibles, transdermal patches, topicals and oils. Cannabis oil is one of the approved ways to ingest medical marijuana. Whether you are looking to make baked goods, infused recipes for drinks, or simply taking the oil sublingually (under the tongue), the possibilities are endless.

Similar to olive, vegetable, and coconut oil, cannabis oil is made through the same chemical extraction process. Cannabis oil is a concentrate made by extracting cannabinoids, such as THC and CBD, from the cannabis plant and putting the extracts into a carrier substance (oil).

What is cannabis oil?

There are so many ways you can use cannabis oil. However, keep in mind the proper dosages for your recipe of choice. The general rule of thumb is to “start low and go slow” so you can find the right dose for you in your meals, drinks or other applications of choice.

There are numerous ways to take cannabis oil that are safe and effective. Here are a few popular ways to help you find relief:

    Under the tongue
    Cannabis oil is generally taken sublingually, where it is absorbed by the mucous membrane under the tongue, eventually making its way into the bloodstream. Unlike pills or other forms of drugs, sublingual medications can enter the bloodstream rapidly and in high concentrations, due to the high vascularity of the cheeks and gums. A few benefits of sublingual marijuana include:

The longer-lasting effect of edibles and capsules make them suitable for many chronic conditions.

Low doses of cannabinoids have not been shown to cause problematic interactions with other drugs. When people start using hundreds or thousands of milligrams of CBD , however, the body may struggle to break down the other pharmaceuticals a person is taking. But such high doses are not normally required for therapeutic benefit when using quality products. People with certain conditions or those who can only access CBD isolates may need to use large doses. Tell your doctor if you are taking high doses of CBD , so that she or he can help manage potential cannabinoid-drug interactions.

Inhalation: Smoking and Vaping

Tinctures involve a solvent like ethanol or sesame oil. [5] Some of the adverse side effects attributed to cannabis extracts may actually be due to ingesting large amounts of the carrier oil.

Ingested cannabinoids are absorbed through the intestines and sent to the liver. It takes about an hour to feel effects when taken on an empty stomach, or up to three hours with food. People should not re-dose THC edibles for at least three hours after ingestion.

Although sublingual sprays can provide rapid and precise dosing, they are often confusing for patients. If you spray CBD oil under the tongue but then swallow immediately, your body will process most of it like an edible. This means that you will receive a lower dose over a longer period of time. With CBD products, this may just make for a weaker effect. But with a THC -rich tincture, people may take another dose after half an hour – thinking they hadn’t had enough – leading to accidental intoxication with THC .