CBD oil should be avoided during pregnancy and breastfeeding. A 2018 study from the American Academy of Pediatrics warned women to avoid marijuana during pregnancy due to the potential risks to a baby’s development. Although it is unclear how CBD contributes, CBD is known to pass through the placental barrier.
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.
Medical marijuana is frequently prescribed to people with intractable (treatment-resistant) pain, including those with terminal cancer. There is some evidence that CBD contributes to this benefit.
There is currently no known “correct” dose of CBD oil. Depending on individual needs and what is being treated, the daily dose may range between 5 and 25 mg.
CBD shows promise in the treatment of anxiety disorders, suggests a 2015 review of studies in the journal Neurotherapeutics. According to the investigators, CBD demonstrated potent anxiolytic (anxiety-relieving) effects in animal research, albeit with counterintuitive results.
CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.
For a long time, researchers were only concerned with studying THC, the psychoactive component that is concentrated in marijuana. However, within the past decade, they have become increasingly interested in the therapeutic benefits of the other compounds found in both varieties, especially cannabidiol (CBD).* It’s important to know that although THC and CBD are the most studied components of cannabis, there are many more chemical compounds found within the plant, such as the phytocannabinoids cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and tetrahydrocannabivarin (THCV), as well as terpenes and flavonoids.
There are many varietals of the Cannabis sativa plant, all of which contain different amounts of THC (the psychoactive component), CBD (a nonpsychoactive component), and other components. Cannabis sativa varietals that have more than 0.3% THC are commonly referred to as marijuana. Hemp is any varietal of Cannabis sativa that contains less than 0.3% THC, and it will not get you high.
As cannabis and hemp become more extensively researched and widely available, we are starting to realize the true therapeutic power of these plants and their derivatives.* But they still generate a lot of confusion. Today, we’re clearing up the murkiness surrounding cannabis products, their differences, and the legality of taking them so we can focus on all the benefits of hemp oil extract as well as the ins and outs of buying and consuming it.*
An introduction to hemp and how it differs from marijuana and CBD.
Researchers have discovered that whole-plant hemp extracts that contain these other compounds are more beneficial than isolated extracts of just CBD or THC, due to a phenomenon called “the entourage effect.”*