Conclusion: CBD may help with depression but more trials are needed.
Most studies investigating if CBD is beneficial at relieving nausea or vomiting, have used a combination of CBD and THC, rather than just CBD alone. A 2016 review found the combination to be either more effective or as effective as a placebo. 14
With a forecasted revenue of over 20 billion by 2024, the CBD market is booming. 1 But what exactly is CBD and how effective is it? We look at 9 proven or possible health benefits of CBD oil.
6. Sleep disorders
Conclusion: CBD may relieve anxiety before events such as public speaking but it is not known what the optimal dose is.
In June 2018, the FDA approved Epidiolex (a plant-based formulation of CBD) to treat seizures for people 2 years of age and older with Dravet syndrome and Lennox-Gastaut syndrome (LGS), which are two rare forms of epilepsy.
CBD (short for cannabidiol) is one of over 200 chemical compounds known as cannabinoids that are found in cannabis. It is the second most prevalent active compound found in cannabis, behind THC (tetrahydrocannabinol), which is the compound in cannabis that has psychoactive properties and gives people a high. 2
Unfortunately, few human trials investigating the use of CBD as a single agent to relieve pain exist, with most trials using a combination of CBD and THC to relieve pain. Notably, Health Canada has approved a combination medication that contains both THC and CBD in a 1:1 ratio for the relief of central nerve-related pain in multiple sclerosis, and cancer pain that is unresponsive to optimized opioid therapy.
Researchers tested the efficacy of inhaled CBD on 24 cigarette smokers who wanted to quit smoking in a 2013 study  that lasted a week. Twelve of the participants who received CBD reduced smoking by about 40%, while the group who received a placebo saw no reduction in the number of cigarettes they smoked.
The research concludes  that CBD could help normalize alterations to the brain areas implicated as a result of psychosis development. CBD improves the patient’s cognition and illness impact on their life quality and global functioning.
Summary: No Proof – there lacks enough academic research to prove that CBD achieves clarity not high.
14.2 May Help Drug (Opioid) Withdrawal & Addiction
However, to heal acne, one should also make sure to avoid stressing out during the repair process because acne is a natural process. While using CBD for acne, you could also incorporate CBD for anxiety during the process to help you calm down and allow your entire skin to repair itself. You can do this by adding a few drops in your drink or food to help manifest CBD’s effect.
This recommendation by the FDA marked an official turn in the long-standing fight to legalize cannabis-derived medicines and products. The recommendation solidified the belief that CBD oil and cannabis-derived products are good and beneficial to human health.
According to a 2018 study, CBD acts on multiple pathways in the brain  affecting the activity of essential mood-regulating chemicals like norepinephrine and serotonin. Serotonin receptor 5HT1A, one of the 5HT receptors, affects anxiety, appetite, sleep, addiction.
Summary: Partly Effective – Some academic research proves that CBD can protect against bone disease and broken bones.
Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.
In addition, the stroke volume (the amount of blood remaining in the heart after a heartbeat) was significantly reduced, meaning that the heart was pumping more efficiently.
This cannabis extract may help treat nerve pain, anxiety, and epilepsy
CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.
In June 2018, the U.S. Food and Drug Administration (FDA) approved Epidiolex, a CBD oral solution used for the treatment of certain rare forms of epilepsy in children under 2—Dravet syndrome and Lennox-Gastaut syndrome. Both are exceptionally rare genetic disorders causing lifelong catastrophic seizures that begin during the first year of life.
There is some evidence that CBD interacts with seizure medications such as Onfi (clobazam) and boosts their concentration in the blood. Further research is needed.