Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.
According to the investigators, men provided 300 mg of CBD exhibited less anxiety than those given a placebo. Interestingly, those provided 100 mg or 600 mg of CBD oil did not.
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
Possible Side Effects
CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
CBD shows promise in the treatment of anxiety disorders, suggests a 2015 review of studies in the journal Neurotherapeutics. According to the investigators, CBD demonstrated potent anxiolytic (anxiety-relieving) effects in animal research, albeit with counterintuitive results.
CBD oil can interact with certain medications, including some drugs used to treat epilepsy. CBD inhibits an enzyme called cytochrome P450 (CYP450), which metabolizes certain drugs. By interfering with CYP450, CBD may either increase the toxicity or decrease the effectiveness of these drugs.
Centers for Disease Control and Prevention: “State Heart Disease and Stroke Prevention Programs Address High Blood Cholesterol.”
Molecules: “Industrial Hemp (Cannabis sativa subsp. sativa) as an Emerging Source for Value-Added Functional Food Ingredients and Nutraceuticals.”
Cannabis and Cannabinoid Research: “A Review of Hemp As Food and Nutritional Supplement.”
Amounts and Dosage
Omega-3 fatty acids abundant in hemp seed oil can help lower blood pressure in people with hypertension (high blood pressure). Research recommends using omega-3 fatty acid supplements along with blood pressure medicine to lower blood pressure.
Experts agree that this 3:1 fatty acid ratio is ideal for health benefits in humans.
Hemp seed oil is extracted from seeds of the hemp plant. The extraction occurs through cold-pressing, similar to the way that olives are cold-pressed to make olive oil.
Current Neurology and Neuroscience Reports: “Cannabis for the Treatment of Epilepsy: an Update.”
Journal of Clinical Investigation: “Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.”
Current Pharmaceutical Biotechnology: “Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.”
Potential Risks of Hemp Oil
Hemp seed oil is used as a remedy for a range of conditions. Some studies show that its nutrients and minerals can contribute to better skin and heart health as well as reduced inflammation. Here’s a deeper look at what the research says about the potential health benefits of hemp oil:
In addition to CBD, Hemp oil contains large amounts of omega-6 and omega-3 fats, which are two types of unsaturated fat s, or “good fats,” and all nine essential amino acids, the materials your body uses to make protein. Here’s more information about nutrients in hemp seed oil and how they may benefit your health.
Hemp seeds also contain these minerals and hemp nutrients:
Hemp oil, also known as hemp seed oil, is made from hemp, a cannabis plant like the drug marijuana but containing little to no tetrahydrocannabinol (THC), the chemical that gets people “high.” Instead of THC, hemp contains cannabidiol (CBD), a chemical that has been used to treat everything from epilepsy to anxiety.