Conclusion: CBD is unlikely to be effective by itself for nausea and vomiting. The combination of THC and CBD does seem to be effective for nausea and vomiting.
Conclusion: CBD shows promise for improving the quality of life in people with Parkinson’s disease but larger trials are needed.
Medically reviewed by Carmen Fookes, BPharm. Last updated on Nov 2, 2020.
9. Nausea and vomiting
Conclusion: CBD may be beneficial at relieving pain but no high-quality human studies prove this.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
CBD has also been investigated for use in other forms of treatment-resistant epilepsy, usually in addition to conventional epilepsy medications. Results varied, but several trials showed CBD significantly reduced seizure frequency by almost 44% in most people. 3
Conclusion: Topical CBD may be beneficial at relieving arthritis but no high-quality human studies prove this.
CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.
For this study, nine healthy men took either 600 mg of CBD or the same dose of a placebo. According to the researcher, those treated with CBD had lower blood pressure before and after exposure to stressful stimuli (including exercise or extreme cold).
The findings suggest that CBD oil may be a suitable complementary therapy for people whose hypertension is complicated by stress and anxiety. However, there is no evidence that CBD oil can treat hypertension on its own or prevent hypertension in people at risk. While stress is known to complicate high blood pressure, it cannot cause hypertension.
Among the few human trials evaluating CBD’s anxiolytic effects was one published in the Brazilian Journal of Psychiatry in 2019. For this study, 57 men were given either CBD oil or a placebo before a public-speaking event. Anxiety was evaluated using physiological measures (such as blood pressure, heart rate, etc.) and a relatively reliable test for mood states known as the Visual Analog Mood Scale (VAMS).
If you are thinking about using CBD oil to treat a health condition, be sure to speak with your healthcare provider to ensure that it is the right option for you.