Potential drug-drug interactions with CBD include:
CBD oil is an extract of Cannabis indica or Cannabis sativa—the same plants that, when dried, make marijuana. CBD oil is believed by some to treat pain, reduce anxiety, and stimulate appetite in the same way that marijuana does, but without its psychoactive effects. CBD has also shown promise in treating certain types of seizures.
According to the investigators, men provided 300 mg of CBD exhibited less anxiety than those given a placebo. Interestingly, those provided 100 mg or 600 mg of CBD oil did not.
Dosage and Preparation
CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.
There are no guidelines for the appropriate use of CBD oil. CBD oil is usually delivered sublingually (under the tongue). Most oils are sold in 30-milliliter (mL) bottles with a dropper cap.
Clinical research has shown that CBD oil can trigger side effects. Severity and type can vary from one person to the next.
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
Nutrition and Metabolism: “The cardiac and haemostatic effects of dietary hempseed.”
One tablespoon (15 milliliters) of hemp seed oil contains:
EuropeanJournal of Lipid Science and Technology: “Physiochemical studies of hemp (Cannabis sativa) seed oil using enzyme-assisted cold-pressing.”
Amounts and Dosage
Journal of Nutraceuticals, Functional and Medical Foods: “The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition.”
Although the hemp and the cannabis (marijuana) plant belong to the same plant family, Cannabis sativa L, they are two different plants and have different compositions. The most notable difference is the amount of tetrahydrocannabinol (THC) present in each plant. THC is the psychoactive portion of the cannabis plant. It’s the chemical that makes you feel “high”.
Lower Blood Pressure
Although hemp seed oil offers many health benefits, it’s important to be aware of the potential risks.
Journal of Clinical Investigation: “Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.”
It’s possible that ingesting CBD-containing oils like hemp oil can cause an upset stomach or diarrhea. Again, when you’re first introducing hemp oil into your diet, start small to see how it impacts you. Reactions may be different from person to person.
Current Pharmaceutical Biotechnology: “Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.”
Potential Risks of Hemp Oil
GW Research Ltd.: “A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6).”
Hemp oil, also known as hemp seed oil, is made from hemp, a cannabis plant like the drug marijuana but containing little to no tetrahydrocannabinol (THC), the chemical that gets people “high.” Instead of THC, hemp contains cannabidiol (CBD), a chemical that has been used to treat everything from epilepsy to anxiety.
Spreading hemp oil on your skin as a topical application can also reduce symptoms and provide relief for several types of skin disorders. One study showed that hemp oil can act as an effective acne treatment, though more research is needed in this area. In addition, consuming hemp seed oil was found to improve symptoms of atopic dermatitis, or eczema, due to the presence of the “good” polyunsaturated fats in the oil.
Although hemp and marijuana come from the same species of cannabis plant, hemp has little to no THC. This means that consuming hemp is legal in the U.S. and will not cause you to become intoxicated or impaired.